Suppr超能文献

沙特阿拉伯利雅得省医院的解毒剂供应情况。

Antidote Availability in Saudi Arabia Hospitals in the Riyadh Province.

机构信息

Pediatric Emergency, King Fahad Medical City, Riyadh, Saudi Arabia.

Pharmacy Department, King Fahad Medical City, Riyadh, Saudi Arabia.

出版信息

Basic Clin Pharmacol Toxicol. 2018 Feb;122(2):288-292. doi: 10.1111/bcpt.12897. Epub 2017 Oct 25.

Abstract

Inadequate antidote stocking is a global problem in hospitals. Insufficient supplies and delays in the administration of antidotes could lead to death and additional potentially negative clinical consequences. Our objective was to determine the availability of antidotes in hospitals listed on the Saudi Ministry of Health website in the Riyadh Province and to evaluate the leading poison in Saudi Arabia. A cross-sectional study was conducted using questionnaires. The questionnaires were distributed to pharmacist directors and emergency room-treating physicians in 17 public hospitals throughout the Riyadh Province. None (0/17) of the pharmacies contained the 24 recommended essential antidotes by the expert consensus guidelines for stocking of antidotes in hospitals. Polyvalent scorpion antivenom, atropine sulphate, calcium gluconate, flumazenil and naloxone hydrochloride were stocked in 94.12% (16/17) of hospitals. 66.67% of patients presented with osmolality, and 55.56% of referral patients with opiates, barbiturates, acetaminophen and salicylate. Our findings have important implications for healthcare institutions and pharmaceutical practices. National practice guidelines are needed to assist pharmacists in selecting appropriate antidotes based on the local pattern of poisoning incidents. Therefore, further study in the Kingdom of Saudi Arabia needs to be completed to fully evaluate the availability of antidotes throughout the country.

摘要

解毒剂储备不足是全球医院普遍存在的问题。解毒剂供应不足和使用延迟可能导致死亡和其他潜在的负面临床后果。我们的目的是确定沙特卫生部网站上列出的利雅得省医院的解毒剂供应情况,并评估沙特阿拉伯的主要中毒药物。本研究采用横断面研究方法,使用问卷进行调查。问卷分发给利雅得省 17 家公立医院的药剂科主任和急诊室治疗医生。17 家医院中没有一家(0/17)药房储备了专家共识指南中建议的 24 种医院解毒剂储备必备解毒剂。多价蝎子抗蛇毒血清、硫酸阿托品、葡萄糖酸钙、氟马西尼和盐酸纳洛酮在 94.12%(16/17)的医院中储备。66.67%的患者就诊时出现渗透压异常,55.56%的转院患者因阿片类药物、巴比妥类药物、对乙酰氨基酚和水杨酸盐中毒。我们的研究结果对医疗机构和药学实践具有重要意义。需要制定国家实践指南,以帮助药剂师根据当地中毒事件的模式选择合适的解毒剂。因此,需要在沙特阿拉伯王国完成进一步的研究,以全面评估全国解毒剂的供应情况。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验