鱼类胃中存在对抗胚胎鸡胃蛋白酶原抗血清有免疫反应的胃蛋白酶原：可能是高等脊椎动物凝乳酶的祖先分子。
Presence of pepsinogens immunoreactive to anti-embryonic chicken pepsinogen antiserum in fish stomachs: possible ancestor molecules of chymosin of higher vertebrates.
作者信息
Yasugi S, Matsunaga T, Mizuno T
机构信息
Zoological Institute, University of Tokyo, Japan.
出版信息
Comp Biochem Physiol A Comp Physiol. 1988;91(3):565-9. doi: 10.1016/0300-9629(88)90636-6.
PMID:2906837
Abstract
- Stomachs of adult teleosts and elasmobranchs reacted to an anti-embryonic chicken pepsinogen antiserum (anti-ECPg) as well as to an anti-adult chicken pepsinogen antiserum (anti-ACPg). 2. Zymograms and immunoblots of stomach extracts revealed that anti-ECPg- and anti-ACPg-reactive substances possess peptic activity. 3. The possible relationship between anti-ECPg-reactive pepsinogens in fish and prochymosins in higher vertebrates is discussed.
摘要
- 成年硬骨鱼和软骨鱼的胃对抗胚胎鸡胃蛋白酶原抗血清（抗ECPg）以及抗成年鸡胃蛋白酶原抗血清（抗ACPg）均有反应。2. 胃提取物的酶谱和免疫印迹显示，抗ECPg和抗ACPg反应性物质具有消化活性。3. 讨论了鱼类中抗ECPg反应性胃蛋白酶原与高等脊椎动物中前凝乳酶之间的可能关系。
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