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轻度创伤性脑损伤患者齿状核红核丘脑束损伤加重:一例报告

Aggravation of an injured dentato-rubro-thalamic tract in a patient with mild traumatic brain injury: A case report.

作者信息

Jang Sung Ho, Kwon Hyeok Gyu

机构信息

Department of Physical Medicine and Rehabilitation, College of Medicine, Yeungnam University, Daegu Department of Physical Therapy, College of Health Sciences, Catholic University of Pusan, Republic of Korea.

出版信息

Medicine (Baltimore). 2017 Oct;96(43):e8253. doi: 10.1097/MD.0000000000008253.

DOI:10.1097/MD.0000000000008253
PMID:29068990
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5671823/
Abstract

RATIONALE

We report on a patient with mild traumatic brain injury (TBI) by follow-up diffusion tensor tractography (DTT), and observed for approximately nine monthsby serial diffusion tensor tractography (DTT).

PATIENT CONCERNS

A 66-year-old male patient was injured in a car crash. Approximately four weeks after the crash, he developed a tremor in the right hand and leg. His symptoms worsened over time.

DIAGNOSES

Approximately six months after the crash, he developed a mild tremor in the left hand. Nine months after the crash, he manifested severe tremor in his right hand, mild resting and intentional tremor in his left hand and both legs, and mild trunkal ataxia.

INTERVENTIONS

N/A.

OUTCOMES

On 3-week DTT, well reconstructed DRTTs were observed in both hemispheres, except for the thinned lower portion of the right DRTT. On 9-month DTT, the right lower DRTT had thinned compared with the 3-week DTT and showed a disruption at the upper portion. The left DRTT showed thinning in the lower portion and tearing in the upper portion compared with 3-week DTT.

LESSONS

Aggravation of an injured DRTT was demonstrated in a patient with mild TBI, using serial DTT examination.

摘要

原理

我们通过随访扩散张量纤维束成像(DTT)报告了一名轻度创伤性脑损伤(TBI)患者,并通过系列扩散张量纤维束成像(DTT)观察了约九个月。

患者情况

一名66岁男性患者在车祸中受伤。车祸后约四周,他右手和右腿出现震颤,症状随时间加重。

诊断

车祸后约六个月,他左手出现轻度震颤。车祸后九个月,他右手出现严重震颤,左手和双腿出现轻度静止性和意向性震颤,以及轻度躯干共济失调。

干预措施

无。

结果

在3周的DTT检查中,除右侧DRTT下部变薄外,双侧半球的DRTT均重建良好。在9个月的DTT检查中,与3周时相比,右侧DRTT下部变薄,上部出现中断。与3周时相比,左侧DRTT下部变薄,上部撕裂。

经验教训

通过系列DTT检查,在一名轻度TBI患者中证实了受伤的DRTT会加重。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c16e/5671823/831b54782c01/medi-96-e8253-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c16e/5671823/831b54782c01/medi-96-e8253-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c16e/5671823/831b54782c01/medi-96-e8253-g001.jpg

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本文引用的文献

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Ataxia and tremor due to lesions involving cerebellar projection pathways: a DTI tractographic study in six patients.小脑投射通路病变所致共济失调和震颤:6例患者的扩散张量成像纤维束示踪研究
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Deep brain stimulation for essential tremor: targeting the dentato-rubro-thalamic tract?
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