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秘鲁接受血液透析的急性肾损伤患者群体中与死亡率相关的因素。

Factors associated with mortality in a population with acute kidney injury undergoing hemodialysis in Peru.

作者信息

Herrera-Añazco Percy, Taype-Rondan Alvaro, Pacheco-Mendoza Josmel, Miranda J Jaime

机构信息

Universidad Peruana de Ciencias Aplicadas.

Universidad Peruana Cayetano Heredia.

出版信息

J Bras Nefrol. 2017 Apr-Jun;39(2):119-125. doi: 10.5935/0101-2800.20170029.

DOI:10.5935/0101-2800.20170029
PMID:29069239
Abstract

INTRODUCTION

Patients with acute kidney injury (AKI) in developing countries are described in a profile of young age, with less comorbidities, with unifactorial, and with a lower mortality compared to patients in developed countries.

OBJECTIVE

To assess mortality in patients with acute kidney injury undergoing hemodialysis (HD) and its associated factors in a developing country setting.

METHODS

Retrospective study. Demographic, clinical, and mortality variables were collected from patients who presented AKI and underwent HD between January 2014 and December 2015 at a national reference hospital in Lima, Peru. Risk ratios (RR) and 95% confidence intervals (95%CI) were estimated through Poisson regressions.

RESULTS

Data from 72 patients with AKI that underwent HD were analyzed, 66.7% of them were < 64 years old, and 40.2% of all patients died undergoing HD. Crude analysis showed higher mortality among those who used vasopressors, but lower mortality among those with creatinine values > 8.9 mg/dL. The adjusted analysis showed that having had a creatinine level of > 8.9 mg/dL, compared to a creatinine level of < 5.2 mg/dL at the time of initiating HD, was associated with 74% less probability of death.

CONCLUSION

Four out of every ten AKI patients undergoing HD die. Higher levels of creatinine were associated with lower probability of mortality.

摘要

引言

与发达国家的患者相比,发展中国家急性肾损伤(AKI)患者的特点是年龄较轻、合并症较少、病因单一且死亡率较低。

目的

评估在发展中国家环境下接受血液透析(HD)的急性肾损伤患者的死亡率及其相关因素。

方法

回顾性研究。收集了2014年1月至2015年12月期间在秘鲁利马一家国家参考医院出现急性肾损伤并接受血液透析的患者的人口统计学、临床和死亡率变量。通过泊松回归估计风险比(RR)和95%置信区间(95%CI)。

结果

分析了72例接受血液透析的急性肾损伤患者的数据,其中66.7%年龄小于64岁,所有患者中有40.2%在血液透析期间死亡。粗略分析显示,使用血管加压药的患者死亡率较高,但肌酐值>8.9mg/dL的患者死亡率较低。调整分析显示,与开始血液透析时肌酐水平<5.2mg/dL相比,肌酐水平>8.9mg/dL与死亡概率降低74%相关。

结论

每十名接受血液透析的急性肾损伤患者中有四人死亡。较高的肌酐水平与较低的死亡概率相关。

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