Gao Fei-Yan, Li Ling, Wang Jiao-Yu, Wang Yan-Li, Sun Guo-Chang
1. School of Chemistry and Life Science Zhejiang Normal University, Jinhua 321004, China; 2. State Key Laboratory Breeding Base for Zhejiang Sustainable Pest and Disease Control, Institute of Plant Protection Microbiology, Zhejiang Academy of Agricultural Sciences, Hangzhou 310021, China.
1. State Key Laboratory Breeding Base for Zhejiang Sustainable Pest and Disease Control, Institute of Plant Protection Microbiology, Zhejiang Academy of Agricultural Sciences, Hangzhou 310021, China; 2. School of Agricultural and Food Sciences, Zhejiang Agriculture and Forest University, Lin'.
Yi Chuan. 2017 Oct 20;39(10):908-917. doi: 10.16288/j.yczz.17-079.
Peroxisomes are cellular organelles present ubiquitously in eukaryotic cells and are involved in β-oxidation, glyoxylate cycle and a variety of biochemical metabolisms. Recently peroxisomes have been demonstrated to play vital roles in the host infection processes by plant fungal pathogens. The biogenesis of peroxisomes requires a category of proteins named peroxins, which are encoded by the PEX genes. So far, more than 10 PEX genes were isolated in phytopathogenic fungi, and significant research efforts are focused on the mechanism of peroxisome formation and the roles of peroxisome in the development and pathogenicity of fungal pathogens. In this review, we summarize the latest advances in peroxisome biogenesis and functions in pathogenic fungi, including the roles of PEXs in life cycle of peroxisome, peroxisome related metabolisms, and fungal development, infection and pathogenicity, in order to provide references for future studies in plant pathogenic fungi and the control of disease.
过氧化物酶体是真核细胞中普遍存在的细胞器，参与β-氧化、乙醛酸循环和多种生物化学代谢过程。最近，过氧化物酶体已被证明在植物真菌病原体的宿主感染过程中发挥重要作用。过氧化物酶体的生物发生需要一类名为过氧化物酶的蛋白质，这些蛋白质由PEX基因编码。到目前为止，在植物病原真菌中已分离出10多个PEX基因，大量研究工作集中在过氧化物酶体形成的机制以及过氧化物酶体在真菌病原体发育和致病性中的作用。在本综述中，我们总结了致病真菌过氧化物酶体生物发生和功能的最新进展，包括PEXs在过氧化物酶体生命周期、过氧化物酶体相关代谢以及真菌发育、感染和致病性中的作用，以便为未来植物病原真菌的研究和病害防治提供参考。
