Department of Tropical Medicine, Tulane School of Public Health and Tropical Medicine, 1440 Canal St, Suite 2309, MC#8317, New Orleans, LA, 70112, USA.
UK Public Health Rapid Support Team-UK PHRST, Public Health England, Wellington House, 133-155 Waterloo Road, London, SE1 8UG, UK.
Curr Top Microbiol Immunol. 2017;411:63-92. doi: 10.1007/82_2017_69.
The 2013 outbreak of Ebola virus disease (EVD) in West Africa constituted a major humanitarian crisis. The outbreak numbered over 28,500 cases, more than 10 times the number cumulatively registered from all previous EVD outbreaks combined, with at least 11,000 deaths, and resulted in billions of dollars of lost economic growth to an already impoverished region. The unprecedented scale of West Africa 2013 took the world by surprise and laid bare deficiencies in our response capacity to complex humanitarian disasters of highly infectious and lethal pathogens. However, the magnitude of West Africa 2013 also provided a unique opportunity and obligation to better understand not only the biology and epidemiology of EVD, but also the many scientific, economic, social, political, ethical, and logistical challenges in confronting emerging infectious diseases in the modern era.
2013 年西非埃博拉病毒病(EVD)疫情构成了重大的人道主义危机。此次疫情病例超过 28500 例,比以往历次 EVD 疫情病例数总和多 10 倍以上,死亡人数至少为 11000 人,使本已贫困的地区损失了数十亿美元的经济增长。2013 年西非疫情规模空前,令世界猝不及防,暴露出我们应对高传染性和致命病原体复杂人道主义灾难的应对能力存在缺陷。然而,西非 2013 年疫情的规模也为我们提供了一个独特的机会和义务,不仅要更好地了解埃博拉病毒的生物学和流行病学,还要更好地了解在现代应对新发传染病时所面临的许多科学、经济、社会、政治、伦理和后勤方面的挑战。