Gazdaru Smaranda, Surbone Anna, Mathevet Patrice, Leyvraz-Recrosio Céline, Primi Marie-Pierre, Vulliemoz Nicolas
Unité de médecine de la reproduction, Département femme-mère-enfant, CHUV, 1011 Lausanne.
Service de gynécologie, Département femme-mère-enfant, CHUV, 1011 Lausanne.
Rev Med Suisse. 2017 Oct 25;13(580):1832-1837.
The development of assisted reproductive technology (ART) has led to the birth of nearly 6 million children since the first IVF baby in 1978. For many years, it was routine practice to transfer multiple embryos in order to obtain the highest pregnancy rates. This strategy has induced a dramatic increase in multiple pregnancies and the associated complications for the mother and the child. Following better awareness of these issues, ART specialists have tried to reduce multiple pregnancy rates with the goal of producing a single, healthy full term baby. Improvement in embryo culture and cryopreservation are the key factors leading to the strategy of elective single embryo transfer (eSET) which represents the best option to achieving this goal. However eSET strategy needs to be implemented in good prognosis patient with good quality embryos.
自1978年首例试管婴儿诞生以来，辅助生殖技术（ART）的发展已使近600万儿童得以出生。多年来，为了获得最高的妊娠率，移植多个胚胎一直是常规做法。这一策略导致多胎妊娠以及母婴相关并发症急剧增加。在对这些问题有了更深入的认识之后，ART专家试图降低多胎妊娠率，目标是生出一个健康的足月单胎婴儿。胚胎培养和冷冻保存技术的改进是促成选择性单胚胎移植（eSET）策略的关键因素，而eSET策略是实现这一目标的最佳选择。然而，eSET策略需要在胚胎质量良好、预后良好的患者中实施。
