Zhang Ji-Shui, Zhang Xiu-Ting, Zou Li-Ping, Zhang Rong, Han Song-Ping, Han Ji-Sheng
Neurology Department, Beijing Children's Hospital Affiliated to Capital Medical University, Beijing 100045, China.
Beijing Tongkang Rehabilitation Center, Zhuozhou 072750, Hebei Province.
Zhen Ci Yan Jiu. 2017 Jun 25;42(3):249-53.
To investigate the clinical efficacy of transcutaneous electrical acupoint stimulation (TEAS) in treating children with autism spectrum disorders.
Forty-one autistic children receiving rehabilitation training were randomized into TEAS (=21) and control (=20) groups. The control group only received rehabilitation training. The TEAS group received both rehabilitation training and TEAS treatment[2 Hz/15 Hz alternating frequencies through two pairs of skin electrodes placed at Hegu (LI 4)-Neiguan (PC 6) on unilateral side, and Zusanli (ST 36)-Sanyinjiao (SP 6) on the contralateral side]. The treatment was given 30 min per day for 12 weeks. The outcome assessment was quantified with a series of rating scales including Autism Behavior Checklist (ABC), Childhood Autism Rating Scale (CARS) and Parent Symptom Questionnaire (PSQ).
(1) The TEAS group showed more significant improvement than the control group in ABC (<0.01). 38.1% effective rate (8/21) was observed in the TEAS group compared to 5.0% (1/20) in the control group (<0.05). The CARS scores of both groups were reduced (<0.0001) after treatment. The TEAS group showed significantly lower score compared to the control group (<0.0001). (2)There was a distinctly reduced PSQ score in both TEAS and control groups (<0.001) after treatment.(3)TEAS intervention showed better effect in children under 6 years old with moderate or severe autistic symptoms.
TEAS intervention can significantly improve the autistic symptoms.
探讨经皮穴位电刺激（TEAS）治疗儿童自闭症谱系障碍的临床疗效。
将41例接受康复训练的自闭症儿童随机分为TEAS组（n = 21）和对照组（n = 20）。对照组仅接受康复训练。TEAS组在接受康复训练的同时接受TEAS治疗[通过两对皮肤电极以2 Hz/15 Hz交替频率进行刺激，一对置于单侧合谷（LI 4）-内关（PC 6），另一对置于对侧足三里（ST 36）-三阴交（SP 6）]。每天治疗30分钟，共12周。采用一系列评定量表进行结果评估，包括自闭症行为量表（ABC）、儿童自闭症评定量表（CARS）和家长症状问卷（PSQ）。
（1）TEAS组在ABC量表评分改善方面比对照组更显著（P<0.01）。TEAS组有效率为38.1%（8/21），对照组为5.0%（1/20）（P<0.05）。两组治疗后CARS评分均降低（P<0.0001），且TEAS组评分显著低于对照组（P<0.0001）。（2）治疗后TEAS组和对照组PSQ评分均明显降低（P<0.001）。（3）TEAS干预对6岁以下中重度自闭症症状儿童效果更佳。
TEAS干预可显著改善自闭症症状。
