经尿道内注射肉毒毒素 A 联合骶神经调节治疗神经源性逼尿肌过度活动症。
Intradetrusor injection of botulinum toxin A and sacral neuromodulation for neurogenic detrusor overactivity.
机构信息
Medical School Paris Île-de-France Ouest, Inserm U1179, Versailles Saint-Quentin University, Versailles, France -
Department of Physical Medicine and Rehabilitation, Raymond-Poincaré AP-HP Hospital, Garches, France -
出版信息
Eur J Phys Rehabil Med. 2017 Dec;53(6):991-997. doi: 10.23736/S1973-9087.17.04978-4. Epub 2017 Oct 25.
Intradetrusor injection of botulinum toxin A and sacral neuromodulation are the two recommended third line treatments for patients with neurogenic detrusor overactivity, before undergoing with surgery. However, only Botox® injection is supported by a high level of evidence allowing its recommendation by all institutional guidelines. Despite few positive results, sacral neuromodulation should be proposed in carefully selected patients. Indeed, other studies remain mandatory to increase its level of evidence necessary for allowing its use in neurogenic detrusor overactivity.
经尿道内注射肉毒毒素 A 和骶神经调节是推荐用于神经源性逼尿肌过度活动患者的两种三线治疗方法，然后再进行手术。然而，只有 Botox®注射得到了高水平证据的支持，所有机构指南都推荐使用。尽管有一些积极的结果，但骶神经调节应该在经过仔细选择的患者中提出。事实上，仍然需要其他研究来提高其在神经源性逼尿肌过度活动中的证据水平，以允许其使用。
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