Department of Pharmacy and Therapeutics, School of Pharmacy, University of Pittsburgh, Pittsburgh, PA, United States; Department of Clinical Pharmacy, School of Pharmacy, Jordan University of Science and Technology, Irbid, Jordan.
School of Medicine, University of Pittsburgh, Pittsburgh, PA, United States.
J Crit Care. 2018 Apr;44:77-81. doi: 10.1016/j.jcrc.2017.10.029. Epub 2017 Oct 19.
To assess costs of intensive care unit (ICU) related pharmacotherapy relative to hospital drug expenditures, and to identify potential targets for cost-effectiveness investigations. We offer the unique advantage of comparing ICU drug costs with previously published data a decade earlier to describe changes over time.
Financial transactions for all ICU patients during fiscal years (FY) 2009-2012 were retrieved from the hospital's data repository. ICU drug costs were evaluated for each FY. ICU departments' charges were also retrieved and calculated as percentages of total ICU charges.
Albumin, prismasate (dialysate), voriconazole, factor VII and alteplase denoted the highest percentages of ICU drug costs. ICU drug costs contributed to an average of 31% (SD 1.0%) of the hospital's total drug costs. ICU drug costs per patient day increased by 5.8% yearly versus 7.8% yearly for non-ICU drugs. This rate was higher for ICU drugs costs at 12% a decade previous. Pharmacy charges contributed to 17.7% of the total ICU charges.
Growth rates of costs per year have declined but still drug expenditures in the ICU are consistently a significant driver in this resource intensive environment with a high impact on hospital drug expenditures.
评估与医院药品支出相比，重症监护病房（ICU）相关药物治疗的成本，并确定成本效益调查的潜在目标。我们提供了一个独特的优势，即可以将 ICU 药物成本与十年前的先前发表的数据进行比较，以描述随时间的变化。
从医院的数据存储库中检索了 2009-2012 财年所有 ICU 患者的财务交易。评估了每个财政年度的 ICU 药物成本。还检索了 ICU 部门的费用，并计算为 ICU 总费用的百分比。
白蛋白、普瑞玛萨特（透析液）、伏立康唑、VII 因子和阿替普酶表示 ICU 药物成本的最高百分比。ICU 药物成本平均占医院总药物成本的 31%（SD 1.0%）。与非 ICU 药物每年增长 7.8%相比，ICU 患者每天的药物成本每年增长 5.8%。这一比率在十年前的 ICU 药物成本中更高，为 12%。药房费用占 ICU 总费用的 17.7%。
每年的成本增长率有所下降，但 ICU 中的药物支出仍然是这种资源密集型环境中的主要驱动因素，对医院的药物支出有重大影响。
