Division of Pediatric Neurology, Women and Children's Hospital of Buffalo, Buffalo, New York; Department of Neurology, Jacobs School of Medicine, State University of New York at Buffalo, Buffalo, New York.
Department of Neurology, Jacobs School of Medicine, State University of New York at Buffalo, Buffalo, New York.
Pediatr Neurol. 2017 Dec;77:5-11. doi: 10.1016/j.pediatrneurol.2017.08.008. Epub 2017 Aug 24.
Alice in Wonderland syndrome is a disorienting neurological condition that affects human perception to the senses of vision, hearing, touch, sensation, and the phenomenon of time. Individuals affected with Alice in Wonderland syndrome can experience alterations in their perception of the size of objects or their own body parts, known as metamorphopsias. It is known to occur in conditions including migraine, epilepsy, and certain intoxicants and infectious diseases. The name refers to Lewis Carrol's well-known children's book Alice's Adventures in Wonderland, in which the title character experiences alterations of sensation in which she felt that her body had grown too tall or too small, or parts of her body were changing shape, size, or relationship to the rest of her body. The syndrome was described in 1952 by Caro Lippman, and given its name in 1955 by John Todd. The metamorphopsias characteristic of this condition are also sometimes referred to as Lilliputian hallucinations, a reference to the fictional island of Lilliput in the novel Gulliver's Travels, written by Jonathan Swift in 1726. As such, many literary and medical publications have roots in the description of this syndrome. The purpose of this review is to summarize the literary and historical significance of Alice in Wonderland syndrome, as well as to provide the reader with a medical overview of the condition.
爱丽丝梦游仙境综合征是一种使人迷失方向的神经系统疾病，会影响人类对视觉、听觉、触觉、感觉等感官以及时间现象的感知。患有爱丽丝梦游仙境综合征的个体可能会经历对物体大小或自身身体部位的感知改变，这种现象被称为视物变形症。已知偏头痛、癫痫和某些中毒和传染病会引起这种综合征。这个名字指的是刘易斯·卡罗尔的著名儿童读物《爱丽丝梦游仙境》，书中的主角经历了感觉的改变，她觉得自己的身体变得太高或太小，或者身体的某些部位在改变形状、大小或与身体其他部位的关系。该综合征于 1952 年由卡罗·利普森描述，并于 1955 年由约翰·托德命名。这种情况下的视物变形症也被称为小人国幻觉，这是对小说《格列佛游记》中虚构岛屿小人国的一种参考，该小说由乔纳森·斯威夫特于 1726 年创作。因此，许多文学和医学出版物都源于对这种综合征的描述。本综述的目的是总结爱丽丝梦游仙境综合征的文学和历史意义，并为读者提供对该病症的医学概述。
