1例IA期非小细胞肺癌患者同时检测到EGFR基因C797S和L858R新发突变 - Suppr

A Case of Concurrent De Novo C797S and L858R EGFR Mutation Detected in Stage IA Non-Small Cell Lung Cancer Patient.

作者信息

Lee Jong Sik, Hur Jae Young, Kim Hee Joung, Lee Kye Young, Kim Wan Seop

机构信息

Lung Cancer Center, Department of Pulmonary Medicine, Konkuk University Medical Center, Konkuk University School of Medicine, Seoul, Republic of Korea.

出版信息

J Thorac Oncol. 2017 Nov;12(11):e179-e181. doi: 10.1016/j.jtho.2017.07.016.

DOI:10.1016/j.jtho.2017.07.016

PMID:29074208

Abstract

摘要

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A Case of Concurrent De Novo C797S and L858R EGFR Mutation Detected in Stage IA Non-Small Cell Lung Cancer Patient.1例IA期非小细胞肺癌患者同时检测到EGFR基因C797S和L858R新发突变

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Activity of epidermal growth factor receptor-tyrosine kinase inhibitors in patients with non-small cell lung cancer harboring rare epidermal growth factor receptor mutations.表皮生长因子受体酪氨酸激酶抑制剂在携带罕见表皮生长因子受体突变的非小细胞肺癌患者中的活性。

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Differential efficacy of cisplatin plus pemetrexed between L858R and Del-19 in advanced EGFR-mutant non-squamous non-small cell lung cancer.晚期 EGFR 突变型非鳞状非小细胞肺癌中 L858R 与 Del-19 患者顺铂联合培美曲塞的疗效差异。

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Somatic mutation analysis of KRAS, BRAF, HER2 and PTEN in EGFR mutation-negative non-small cell lung carcinoma: determination of frequency, distribution pattern and identification of novel deletion in HER2 gene from Indian patients.EGFR 突变阴性非小细胞肺癌中 KRAS、BRAF、HER2 和 PTEN 的体细胞突变分析：印度患者中突变频率、分布模式的确定及 HER2 基因新型缺失的鉴定

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Non-small-cell lung cancers with kinase domain mutations in the epidermal growth factor receptor are sensitive to ionizing radiation.具有表皮生长因子受体激酶结构域突变的非小细胞肺癌对电离辐射敏感。

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A Case of Concurrent De Novo C797S and L858R EGFR Mutation Detected in Stage IA Non-Small Cell Lung Cancer Patient.

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