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严重肥胖青少年接受减肥手术前尿失禁的前瞻性评估。

Prospective evaluation of urinary incontinence in severely obese adolescents presenting for weight loss surgery.

机构信息

Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.

University of Colorado Denver, Aurora, Colorado.

出版信息

Surg Obes Relat Dis. 2018 Feb;14(2):214-218. doi: 10.1016/j.soard.2017.09.510. Epub 2017 Sep 14.

Abstract

BACKGROUND

Obesity has been associated with daytime urinary incontinence (UI), likely due to increased intra-abdominal pressure.

OBJECTIVES

To assess incontinence symptoms in severely obese adolescents before and 3 years after bariatric surgery.

SETTING

Tertiary care pediatric hospitals in the United States.

METHODS

The Teen-Longitudinal Assessment of Bariatric Surgery is a prospective, multicenter study designed to evaluate efficacy and safety of bariatric surgery in adolescents. Patients<19 years of age undergoing bariatric surgery at 5 centers between 2007 and 2012 were enrolled. Trained study staff collected baseline and postoperative anthropometric and clinical data. Presence and severity of UI were determined by standardized interview.

RESULTS

A total of 242 patients (76% female) were evaluated at baseline. The mean age was 17.1 years at baseline, and 72% were of white race. The preoperative median body mass index was 50.5 kg/m. At baseline, 18% of females and 7% of males reported UI. Prediction analysis at baseline indicated that females, white race, and increasing body mass index had greater odds for UI. UI prevalence in females and males decreased to 7% and 0%, respectively, at 6 months after surgery (P<.01) and remained stable out to 36 months postoperatively. Furthermore, older patients were less likely to achieve 3-year UI remission or improvement.

CONCLUSIONS

In adolescents undergoing bariatric surgery, UI was more common in females than in males. Incontinence status significantly improved by 6 months and was durable to 3 years after surgery, suggesting that bariatric surgery favorably affects anatomic or physiologic mechanisms of bladder control in both males and females.

摘要

背景

肥胖与日间尿失禁(UI)有关,这可能是由于腹内压增加所致。

目的

评估严重肥胖青少年在接受减肥手术后之前和 3 年的失禁症状。

地点

美国的三级保健儿科医院。

方法

青少年减肥手术纵向评估是一项前瞻性,多中心研究,旨在评估减肥手术对青少年的疗效和安全性。2007 年至 2012 年间,在 5 个中心接受减肥手术的年龄<19 岁的患者被纳入研究。经过培训的研究人员收集了基线和术后的人体测量学和临床数据。通过标准化访谈确定 UI 的存在和严重程度。

结果

共有 242 名患者(76%为女性)进行了基线评估。基线时的平均年龄为 17.1 岁,72%为白人。术前中位数体重指数为 50.5kg/m。基线时,18%的女性和 7%的男性报告有 UI。基线预测分析表明,女性,白种人以及体重指数的增加与 UI 的可能性更大相关。手术后 6 个月,女性和男性的 UI 发生率分别降至 7%和 0%(P<.01),并在术后 36 个月保持稳定。此外,年龄较大的患者不太可能实现 3 年的 UI 缓解或改善。

结论

在接受减肥手术的青少年中,女性比男性更常见 UI。失禁状况在 6 个月时明显改善,并在手术后 3 年内保持稳定,这表明减肥手术对男性和女性的膀胱控制的解剖或生理机制均有有利影响。

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本文引用的文献

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Kidney stones are common after bariatric surgery.肾结石在减肥手术后很常见。
Kidney Int. 2015 Apr;87(4):839-45. doi: 10.1038/ki.2014.352. Epub 2014 Oct 29.
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The increasing pediatric stone disease problem.小儿结石病问题日益严重。
Ther Adv Urol. 2011 Feb;3(1):3-12. doi: 10.1177/1756287211400491.
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Effect of gastric bypass surgery on kidney stone disease.胃旁路手术对肾结石病的影响。
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