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[Gene amplification and rearrangement of murine ribosomal RNA in virus-induced Rauscher leukemia].

作者信息

Domninskiĭ D A, Pokrovskaia E S, Smirnova I A, Butenko Z A, Grineva N I

出版信息

Eksp Onkol. 1988;10(6):17-21.

PMID:2907474
Abstract

Using as a hybridization probe cDNA 35s RNA from the Rauscher leukemia cells, a part of rRNA gene cluster from the gene library of mice C-1 erythroleukemia cells has been cloned. Fragment 6.7 kb recloned into pUC19 rRNA was used as a probe to analyse organization of rRNA genes of mice with RL. The observed amplification and rearrangement in genome DNA of spleen cells are determined by a new type of their rRNA genes rearrangement in the nontranscribed as well as in the transcribed part of rRNA.

摘要

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