在麻醉的自发性高血压大鼠中，局部血管舒张是对内皮素血流动力学反应的一个显著特征。 - Suppr

Suppr

超能文献

Regional vasodilation is a prominent feature of the haemodynamic response to endothelin in anaesthetized, spontaneously hypertensive rats.

作者信息

Wright C E, Fozard J R

机构信息

Preclinical Research Department, Sandoz Ltd., Basel, Switzerland.

出版信息

Eur J Pharmacol. 1988 Oct 11;155(1-2):201-3. doi: 10.1016/0014-2999(88)90425-6.

DOI:10.1016/0014-2999(88)90425-6

PMID:2907490

Abstract

摘要

相似文献

Regional vasodilation is a prominent feature of the haemodynamic response to endothelin in anaesthetized, spontaneously hypertensive rats.在麻醉的自发性高血压大鼠中，局部血管舒张是对内皮素血流动力学反应的一个显著特征。

Eur J Pharmacol. 1988 Oct 11;155(1-2):201-3. doi: 10.1016/0014-2999(88)90425-6.

Experimental hypertension produces diverse changes in the regional vascular responses to endothelin-1 in the rabbit and the rat.实验性高血压会使家兔和大鼠局部血管对内皮素-1的反应产生多种变化。

J Hypertens. 1994 Nov;12(11):1225-34.

Differential haemodynamic effects of endothelin receptor antagonist, SB 209670, in conscious hypertensive and normotensive rats.内皮素受体拮抗剂SB 209670对清醒高血压大鼠和正常血压大鼠的血流动力学差异影响。

Eur J Pharmacol. 1999 Sep 17;381(1):13-21. doi: 10.1016/s0014-2999(99)00536-1.

Differences in regional vascular sensitivity to endothelin-1 between spontaneously hypertensive and normotensive Wistar-Kyoto rats.自发性高血压大鼠与正常血压的Wistar-Kyoto大鼠之间区域血管对内皮素-1敏感性的差异。

Br J Pharmacol. 1990 May;100(1):107-13. doi: 10.1111/j.1476-5381.1990.tb12060.x.

Regional vasodilation to endothelin-1 is mediated by a non-ETA receptor subtype in the anaesthetized rat: effect of BQ-123 on systemic haemodynamic responses.麻醉大鼠中内皮素-1引起的局部血管舒张由非ETA受体亚型介导：BQ-123对全身血流动力学反应的影响

Eur J Pharmacol. 1992 Oct 20;221(2-3):315-24. doi: 10.1016/0014-2999(92)90718-j.

Effects of dipeptidyl peptidase iv inhibition on arterial blood pressure.二肽基肽酶IV抑制对动脉血压的影响。

Clin Exp Pharmacol Physiol. 2008 Jan;35(1):29-34. doi: 10.1111/j.1440-1681.2007.04737.x.

Calcium antagonists: systemic and regional haemodynamic effects in conscious spontaneously hypertensive rats (SHR).钙拮抗剂：清醒自发性高血压大鼠（SHR）的全身和局部血流动力学效应

J Hypertens Suppl. 1984 Dec;2(3):S527-9.

The role of nitric oxide in the regional vasodilator effects of endothelin-1 in the rat.一氧化氮在大鼠内皮素-1区域血管舒张作用中的作用。

Br J Pharmacol. 1992 Mar;105(3):744-50. doi: 10.1111/j.1476-5381.1992.tb09049.x.

In vivo pharmacological characterization of the non-peptide endothelin receptor antagonist SB 209670.非肽类内皮素受体拮抗剂SB 209670的体内药理学特性

Br J Pharmacol. 1995 Jan;114(2):405-13. doi: 10.1111/j.1476-5381.1995.tb13241.x.

Regional haemodynamic responses to pituitary adenylate cyclase-activating polypeptide and vasoactive intestinal polypeptide in conscious rats.清醒大鼠对垂体腺苷酸环化酶激活多肽和血管活性肠肽的局部血流动力学反应。

Br J Pharmacol. 1994 Feb;111(2):589-97. doi: 10.1111/j.1476-5381.1994.tb14778.x.

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Orthogonal Peptide-Templated Labeling Elucidates Lateral ET R/ET R Proximity and Reveals Altered Downstream Signaling.正交肽模板标记阐明了侧向 ET R/ET R 接近度，并揭示了改变的下游信号。

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Intravascular Endothelin-1 does not trigger or increase susceptibility to Spreading Depolarizations.血管内皮素-1 不会引发或增加传播性去极化的易感性。

J Headache Pain. 2020 Oct 27;21(1):127. doi: 10.1186/s10194-020-01194-3.

The heart as an extravascular target of endothelin-1 in particulate matter-induced cardiac dysfunction.在颗粒物诱导的心脏功能障碍中，心脏作为内皮素-1的血管外靶点。

Pharmacol Ther. 2016 Sep;165:63-78. doi: 10.1016/j.pharmthera.2016.05.006. Epub 2016 May 21.

Endothelin.内皮素

Pharmacol Rev. 2016 Apr;68(2):357-418. doi: 10.1124/pr.115.011833.

Susceptibility of juvenile and adult blood-brain barrier to endothelin-1: regulation of P-glycoprotein and breast cancer resistance protein expression and transport activity.幼年期和成年期血脑屏障对内皮素-1的敏感性：P-糖蛋白和乳腺癌耐药蛋白表达和转运活性的调节。

J Neuroinflammation. 2012 Dec 19;9:273. doi: 10.1186/1742-2094-9-273.

Endothelin-converting enzyme-2 is increased in Alzheimer's disease and up-regulated by Abeta.内皮素转化酶-2在阿尔茨海默病中增加，并被β-淀粉样蛋白上调。

Am J Pathol. 2009 Jul;175(1):262-70. doi: 10.2353/ajpath.2009.081054. Epub 2009 Jun 18.

Endothelin-1 reduces p-glycoprotein transport activity in an in vitro model of human adult blood-brain barrier.内皮素-1在成人血脑屏障体外模型中降低P-糖蛋白转运活性。

Cell Mol Neurobiol. 2008 Nov;28(7):915-21. doi: 10.1007/s10571-008-9277-y. Epub 2008 Apr 1.

Eyeing endothelins: a cellular perspective.审视内皮素：细胞视角

Mol Cell Biochem. 2003 Nov;253(1-2):71-88. doi: 10.1023/a:1026005418874.

The nitric oxide-endothelin-1 connection.一氧化氮-内皮素-1关联

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