Christ Shawn E, Stichter Janine P, O'Connor Karen V, Bodner Kimberly, Moffitt Amanda J, Herzog Melissa J
Department of Psychological Sciences, University of Missouri, Columbia, MO, USA.
Thompson Center for Autism & Neurodevelopmental Disorders, University of Missouri, Columbia, MO, USA.
Autism Res Treat. 2017;2017:5843851. doi: 10.1155/2017/5843851. Epub 2017 Sep 17.
Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by impairments in social communication. It has been postulated that such difficulties are related to disruptions in underlying cognitive processes such as executive function. The present study examined potential changes in executive function performance associated with participation in the Social Competence Intervention (SCI) program, a short-term intervention designed to improve social competence in adolescents with ASD. Laboratory behavioral performance measures were used to separately evaluate potential intervention-related changes in individual executive function component processes (i.e., working memory, inhibitory control, and cognitive flexibility) in a sample of 22 adolescents with ASD both before and after intervention. For comparison purposes, a demographically matched sample of 14 individuals without ASD was assessed at identical time intervals. Intervention-related improvements were observed on the working memory task, with gains evident in spatial working memory and, to a slightly lesser degree, verbal working memory. Significant improvements were also found for a working memory-related aspect of the task switching test (i.e., mixing costs). Taken together, these findings provide preliminary support for the hypothesis that participation in the SCI program is accompanied by changes in underlying neurocognitive processes such as working memory.
自闭症谱系障碍(ASD)是一种神经发育障碍,其特征是社交沟通受损。据推测,此类困难与诸如执行功能等潜在认知过程的中断有关。本研究考察了参与社交能力干预(SCI)项目相关的执行功能表现的潜在变化,该项目是一项旨在提高患有ASD的青少年社交能力的短期干预措施。在干预前后,使用实验室行为表现测量方法,分别评估了22名患有ASD的青少年样本中各个执行功能组成过程(即工作记忆、抑制控制和认知灵活性)与干预相关的潜在变化。为作比较,在相同时间间隔对14名无ASD的人口统计学匹配样本进行了评估。在工作记忆任务上观察到了与干预相关的改善,在空间工作记忆方面有明显提升,言语工作记忆方面的提升程度稍小。在任务转换测试中与工作记忆相关的一个方面(即混合成本)也发现了显著改善。综上所述,这些发现为以下假设提供了初步支持:参与SCI项目伴随着诸如工作记忆等潜在神经认知过程的变化。