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睡眠剥夺后的皮质醇觉醒反应:皮质醇觉醒反应是对觉醒的“反应”还是一种昼夜节律过程?

The cortisol awakening response after sleep deprivation: Is the cortisol awakening response a "response" to awakening or a circadian process?

作者信息

Vargas Ivan, Lopez-Duran Nestor

机构信息

University of Pennsylvania, USA.

University of Michigan, USA.

出版信息

J Health Psychol. 2020 Jun;25(7):900-912. doi: 10.1177/1359105317738323. Epub 2017 Oct 27.

DOI:10.1177/1359105317738323
PMID:29076400
Abstract

This study tested whether the cortisol awakening response is dependent on the transition from sleep to awakening, or alternatively, a circadian-driven process that is independent of awakening. A total of 40 participants were randomly assigned to either a total sleep deprivation or a sleep condition. Salivary cortisol was also assessed. Participants in the sleep condition demonstrated a traditional cortisol awakening response, whereas participants in the total sleep deprivation condition showed no increases in morning cortisol. These results are consistent with the notion that if circadian-driven processes are related to the cortisol awakening response, they may only be activated when awakening occurs or is anticipated.

摘要

本研究测试了皮质醇觉醒反应是取决于从睡眠到觉醒的转变,还是相反,是一个独立于觉醒的昼夜节律驱动过程。共有40名参与者被随机分配到完全睡眠剥夺组或睡眠组。同时也对唾液皮质醇进行了评估。睡眠组的参与者表现出传统的皮质醇觉醒反应,而完全睡眠剥夺组的参与者早晨皮质醇没有增加。这些结果与以下观点一致:如果昼夜节律驱动过程与皮质醇觉醒反应有关,那么它们可能只在觉醒发生或被预期时才被激活。

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