From the Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD.
Clin Nucl Med. 2017 Dec;42(12):968-970. doi: 10.1097/RLU.0000000000001859.
A 28-year-old man with history of anaplastic oligodendroglimoma in the left frontal lobe presented with worsening right leg weakness 2 months after surgical resection. MRI of the brain and spine demonstrated a new mass in the left parietal lobe, as well as extraneural osseous metastases. FDG PET scan subsequently showed widespread extraneural metastatic disease. Extraneural metastases from primary brain tumors are a rare occurrence, although anaplastic oligodendroglioma has a propensity for spreading in such a manner. FDG PET can effectively stage patients with extraneural metastases from anaplastic oligodendroglioma by detecting metastatic disease in sites such as the skeleton and liver.
一位 28 岁男性，曾患有左额叶间变性少突胶质细胞瘤，在手术切除后 2 个月出现右腿无力加重。脑部和脊柱的 MRI 显示左顶叶有新的肿块，以及神经外骨骼转移。随后的 FDG PET 扫描显示广泛的神经外转移性疾病。尽管间变性少突胶质细胞瘤有这种扩散倾向，但原发脑肿瘤的神经外转移仍然很少见。FDG PET 通过检测骨骼和肝脏等部位的转移病灶，可有效地对间变性少突胶质细胞瘤的神经外转移患者进行分期。
