Han Naihan, Wang Wenshuang, Lu Danrong, Wang Han, Ma Xinying, Fan Xiaopeng, Li Fuchuan
National Glycoengineering Research Center, and Shandong Provincial Key Laboratory of Carbohydrate Chemistry and Glycobiology, Shandong University, Jinan 250100, P. R. China.
Chem Commun (Camb). 2017 Nov 9;53(90):12209-12212. doi: 10.1039/c7cc06305a.
Based on multiple interactions and fluorescence quenching, we report a novel homogeneous detection method for Glypican-3 which shows a series of significant advantages, including low cost, ease of preparation, rapid response, and high sensitivity and has great potential in the clinical diagnosis of hepatocellular carcinoma and proteoglycan detection.
基于多重相互作用和荧光猝灭，我们报道了一种用于检测磷脂酰肌醇蛋白聚糖-3的新型均相检测方法，该方法具有一系列显著优点，包括成本低、易于制备、响应迅速、灵敏度高，在肝细胞癌的临床诊断和蛋白聚糖检测方面具有巨大潜力。
