Vanderhasselt M -A, Dedoncker J, Arns M, Baeken C
Tijdschr Psychiatr. 2017;59(10):594-599.
The causal influence of cortico-subcortical connectivity by means of brain stimulation seems to be an effective biological treatment in psychiatric patients.
To review the working mechanisms and moderating factors of two non-invasive brain stimulation techniques (NIBS), namely repetitive transcranial magnetic stimulation (rTMS) and transcranial direct current stimulation (tDCS).
We reviewed the current literature on the use of nibs in neuropsychiatric disorders.
First of all, stimulation parameters (location of the stimulation, intensity and duration of the stimulation, number of sessions) are important for the effect of nibs. Secondly, it is important to consider the non-specific neuroplasticity that results from NIBS. Thirdly, recent studies suggest that NIBS should be combined with neurobehavioral interventions, namely cognitive interventions, for the purpose of modulating specific neural processes (i.e. specific neuroplasticity).
If we want to improve the NIBS treatment in neuropsychiatric patients, we need to consider the factors that influence the patients' response to treatment with rTMS and tDCS.
通过脑刺激对皮质-皮质下连接性的因果影响似乎是精神疾病患者一种有效的生物治疗方法。
综述两种非侵入性脑刺激技术（NIBS），即重复经颅磁刺激（rTMS）和经颅直流电刺激（tDCS）的作用机制及调节因素。
我们回顾了当前关于NIBS在神经精神疾病中应用的文献。
首先，刺激参数（刺激部位、刺激强度和持续时间、疗程数）对NIBS的效果很重要。其次，考虑NIBS产生的非特异性神经可塑性很重要。第三，最近的研究表明，为了调节特定神经过程（即特定神经可塑性），NIBS应与神经行为干预，即认知干预相结合。
如果我们想改善神经精神疾病患者的NIBS治疗，我们需要考虑影响患者对rTMS和tDCS治疗反应的因素。
