Division of Neurology, Department of Medicine and Therapeutics, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, Hong Kong.
Neuroscience Research Center and Department of Neurology, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan, ROC.
Neurosci Lett. 2020 Feb 6;719:133437. doi: 10.1016/j.neulet.2018.02.045. Epub 2018 Feb 21.
Transcranial non-invasive brain stimulation (NIBS) has been widely applied in basic research and clinical intervention in the past few decades. It modulates cortical excitability through varies combinations of current form, stimulation position, strength, frequency, duration and intervals. In this review, protocols of different types of NIBS and their aftereffect are introduced. Moreover, evidences in physiology, pharmacology and behavior response are provided to support the effects of NIBS are plasticity-like effects because of their common mechanisms of synaptic plasticity. This is further confirmed by experiments on small animals at the cellular level.
经颅无创脑刺激（NIBS）在过去几十年中已广泛应用于基础研究和临床干预。它通过改变电流形式、刺激位置、强度、频率、持续时间和间隔等组合来调节皮质兴奋性。在这篇综述中，介绍了不同类型的 NIBS 及其后续效应的方案。此外，还提供了生理学、药理学和行为反应方面的证据，以支持 NIBS 的效果是类似可塑性的效应，因为它们具有共同的突触可塑性机制。这在细胞水平上的小动物实验中得到了进一步证实。
