Kotzias Georgios, Agunbiade Modupe, Isaac Leon, Khaladj Morteza
J Am Podiatr Med Assoc. 2017 Sep;107(5):461-466. doi: 10.7547/15-079.
Lymphangioma-like Kaposi's sarcoma (LLKS) is a rare histologic variant of KS. Kaposi's sarcoma is also known as human herpesvirus type 8. The clinical presentation of the LLKS lesion is highly unusual and similar to that of classic KS but with multinodular vascular tumors and lymphedema. We present a 63-year-old native Haitian man with multiple slowly progressive exophytic ulcerated lesions covering more than 60% of his left lower extremity with no systemic involvement. Much confusion surrounded the clinical presentation of these wounds, and we postulated several differential diagnoses. Herein we describe the evaluation, clinical appearance, and progression of LLKS. Due to the rarity of LLKS, treating physicians need to be aware of the clinical presentation and diagnostic criteria of this variant. Despite being incurable, early diagnosis of LLKS can lead to long-term treatment options and a major reduction in symptoms.
淋巴管瘤样卡波西肉瘤（LLKS）是卡波西肉瘤一种罕见的组织学变体。卡波西肉瘤也被称为人类8型疱疹病毒。LLKS病变的临床表现非常不寻常，与经典卡波西肉瘤相似，但有多个结节状血管肿瘤和淋巴水肿。我们报告一例63岁的海地男性，其左下肢有多个缓慢进展的外生性溃疡病变，面积超过左下肢的60%，无全身受累。这些伤口的临床表现存在很多混淆，我们提出了几种鉴别诊断。在此我们描述LLKS的评估、临床表现及病情进展。由于LLKS罕见，治疗医生需要了解这种变体的临床表现和诊断标准。尽管无法治愈，但LLKS的早期诊断可带来长期治疗选择并显著减轻症状。
