Bischoff Peter, Gastmeier Petra
Institut für Hygiene und Umweltmedizin, Charité - Universitätsmedizin Berlin, Deutschland.
Zentralbl Chir. 2017 Oct;142(5):516-523. doi: 10.1055/s-0043-120575. Epub 2017 Oct 27.
Surgical site infections range between the most commonly and second most commonly reported health-care-associated infections worldwide, depending on the analysis. They are associated with increased morbidity and mortality. Not only for the individual patient, the negative consequences of acquiring a surgical site infection affect the patient's relatives, the hospital and health systems in general. In vascular surgery, gram-positive pathogens of the normal flora of the patient's skin and mucosa (nose/throat) represent the almost half of the number of pathogens detected at the infected surgical site. Staphylococcus aureus itself accounts for about one third of these positive samples. Several general and more specific infection prevention and control measures exist, which when applied consistently, reliably, and in a timely manner protects patients and health workers, strengthens the health systems, and optimizes financial resources. In 2016 the World Health Organization launched the first Global Guidelines for the Prevention of surgical site infections. This guideline provides a comprehensive range of evidence-based recommendations for interventions related to the prevention of surgical site infections during the pre-, intra-, and postoperative periods. This article points out the value of this guideline and highlights relevant infection prevention and control measures with a special focus on the evidence in vascular surgery. Among generally applicable recommendations and measures, in the field of vascular surgery, a special focus should be put on the interventions aiming at the reduction of the patient's flora on the skin and mucosa (nose/throat). This is relevant with regard to the relatively high percentage of pathogens being associated with surgical site infections in this field of surgery, and which are normally residing on these tissues. These measures compromise preoperative bathing or showering with soap, decolonization of Staphylococcus aureus in nasal carriers undergoing surgery with mupirocin ointment with or without CHG body wash or surgical skin preparation with an alcohol-based solution containing an antiseptic compound. Surgeons should closely cooperate with colleagues from other disciplines, the infection prevention and control team as well as with the hospital management in order to implement the infection prevention and control measures into the daily routine. Step-by-step implementation should be based upon the local needs and specifications.
根据分析结果,手术部位感染在全球范围内是最常报告和第二常报告的医疗保健相关感染之一。它们与发病率和死亡率的增加有关。手术部位感染不仅对个体患者有负面影响,对患者的亲属、医院及整个卫生系统都会产生不良后果。在血管外科手术中,患者皮肤和黏膜(鼻子/喉咙)正常菌群中的革兰氏阳性病原体占感染手术部位检测到的病原体数量的近一半。金黄色葡萄球菌本身约占这些阳性样本的三分之一。存在一些一般的和更具体的感染预防与控制措施,若能始终如一地、可靠且及时地应用这些措施,就能切实保护患者和医护人员,加强卫生系统,并优化财政资源。2016年,世界卫生组织发布了首份《预防手术部位感染全球指南》。该指南针对术前、术中和术后预防手术部位感染的干预措施提供了一系列全面的循证建议。本文指出了该指南的价值,并特别关注血管外科的相关证据,强调了相关的感染预防与控制措施。在一般适用的建议和措施中,在血管外科领域,应特别关注旨在减少患者皮肤和黏膜(鼻子/喉咙)菌群的干预措施。鉴于该手术领域中与手术部位感染相关的病原体比例相对较高,且这些病原体通常存在于这些组织中,这一点至关重要。这些措施包括术前用肥皂洗澡或淋浴、对接受手术的鼻腔金黄色葡萄球菌携带者使用莫匹罗星软膏进行去定植,可搭配或不搭配含氯己定的沐浴露,或使用含有抗菌化合物的酒精基溶液进行手术皮肤准备。外科医生应与其他学科的同事、感染预防与控制团队以及医院管理层密切合作,以便将感染预防与控制措施落实到日常工作中。应根据当地需求和具体情况逐步实施。