Arnall Justin R, Petro Robin, Patel Jai N, Kennedy LeAnne
1 Levine Cancer Institute, 2351 Carolinas Healthcare System , Charlotte, USA.
2 Comprehensive Cancer Center, Wake Forest Baptist Health, Winston-Salem, USA.
J Oncol Pharm Pract. 2019 Jan;25(1):179-186. doi: 10.1177/1078155217738324. Epub 2017 Oct 27.
The implementation, benefits, and challenges of clinical pharmacist services within a Precision Medicine Program for cancer patients are described. By relating the practice model that was developed, this report may further encourage pharmacists at cancer centers nationally to be involved and lead precision-based care in the oncology setting.
A clinical pharmacist was integrated into a Precision Medicine Program for oncology patients using somatic testing to identify actionable mutations and apply targeted therapy to malignancies. This pharmacist served as a drug resource for the program's molecular tumor board and oncologists seeking precision-based oncologic strategies. The pharmacist was a facilitator of drug assistance and dispensing in collaboration with the specialty pharmacy and provided care to 14 oncology patients receiving precision-based therapies. The clinical pharmacist was readily accepted as an addition to the team by both oncologists and patients and the experience served as an important learning opportunity.
The success of integrating this precision medicine pharmacist into a newly formed Precision Medicine Program and the model it can serve as may be considered for other cancer centers that may or may not have easily accessible pharmacogenomic experts and resources. This service highlights the importance of pharmacist care in such a program and the various opportunities for integration. Oncology clinical pharmacists should seek to integrate into Precision Medicine Programs and systems directing this care and develop their knowledge and understanding of genomics to continue providing the highest level of cancer care as a pivotal member of the cancer care team.
描述临床药师服务在癌症患者精准医疗项目中的实施情况、益处及挑战。通过阐述所建立的实践模式,本报告可能会进一步鼓励全国癌症中心的药师参与并引领肿瘤学环境中基于精准医疗的护理工作。
一名临床药师被纳入针对肿瘤患者的精准医疗项目,该项目利用体细胞检测来识别可操作的突变,并将靶向治疗应用于恶性肿瘤。这位药师为该项目的分子肿瘤委员会以及寻求基于精准医疗的肿瘤学策略的肿瘤学家提供药物资源。该药师与专科药房合作,促进药物援助和配药工作,并为14名接受基于精准医疗的治疗的肿瘤患者提供护理。临床药师很容易被肿瘤学家和患者接纳为团队的一员,这段经历成为了一个重要的学习机会。
对于其他可能有或没有容易获取的药物基因组学专家和资源的癌症中心,可以考虑将这位精准医疗药师成功纳入新成立的精准医疗项目及其可作为的模式。这项服务凸显了药师护理在这样一个项目中的重要性以及各种整合机会。肿瘤临床药师应寻求融入指导此类护理的精准医疗项目和系统,发展他们对基因组学的知识和理解,以继续作为癌症护理团队的关键成员提供最高水平的癌症护理。