Shrestha Shibu, Watts Gemma, Geiger Susi
School of Population Health, RCSI University of Medicine and Health Sciences, Dublin, Ireland.
School of Business, University College Dublin, Dublin, Ireland.
Crit Public Health. 2025 Jun 28;35(1):2520410. doi: 10.1080/09581596.2025.2520410. eCollection 2025.
Personalised medicine is widely utilised in oncology, and healthcare personnel are its main gatekeepers and implementers. This scoping review provides insights into the knowledge and attitudes of healthcare personnel toward personalised medicine for cancer, barriers and challenges faced, and innovative practices employed for the provision of personalised medicine. Extensive database searches identified 19,972 studies, of which 50 studies were included in the final review. The data was charted by two reviewers and analysed thematically. The knowledge of healthcare personnel of personalised medicine was mixed, with some studies reporting overall good knowledge ( = 2) while some reported poor knowledge among healthcare personnel ( = 4). There was high interest (63-95%) in furthering education and training in personalised medicine ( = 6). The commonly reported barriers and challenges were: limited reimbursement and insurance coverage mechanism ( = 11); insufficient education and training ( = 10); and lack of trained personnel to provide the service ( = 7). The innovations identified emphasised enhancing the skills and capacity of the existing workforce as well as using technologies to assist in timely decision-making. Overall, gaps were identified at the human resource, institutional, and systemic levels, which will need to be addressed to improve the provision of personalised medicine and healthcare personnel's confidence levels.
个性化医疗在肿瘤学中得到广泛应用，医护人员是其主要把关者和实施者。本范围综述深入探讨了医护人员对癌症个性化医疗的知识和态度、面临的障碍与挑战以及提供个性化医疗所采用的创新做法。通过广泛的数据库检索，共识别出19972项研究，其中50项研究纳入最终综述。数据由两名评审员制表并进行主题分析。医护人员对个性化医疗的了解参差不齐，一些研究报告称总体了解情况良好（n = 2），而另一些研究则报告医护人员的了解情况较差（n = 4）。对个性化医疗继续教育和培训的兴趣很高（63%-95%）（n = 6）。常见的障碍和挑战包括：报销和保险覆盖机制有限（n = 11）；教育和培训不足（n = 10）；缺乏提供该服务的专业人员（n = 7）。所确定的创新措施强调提高现有工作人员的技能和能力，以及利用技术辅助及时决策。总体而言，在人力资源、机构和系统层面均发现了差距，需要加以解决，以改善个性化医疗的提供情况和医护人员的信心水平。
