Suzuki J, Sakamoto T, Hada Y, Amano K, Takahashi H, Hasegawa I, Sugimoto T
Second Department of Internal Medicine, Faculty of Medicine, University of Tokyo.
J Cardiol. 1988 Jun;18(2):415-23.
The prevalence of Still's murmur was examined by phonocardiographic study, and the clinical significance of this murmur was investigated using pharmacodynamic phonocardiography and echocardiography. Still's murmur was present in 224 of 9,478 cases (2.4%) in school children. Its prevalence was 143 in 4,524 (3.2%) in elementary school children and this was significantly greater than that in middle school youngsters who numbered 81 among 4,954 (1.6%) (p less than 0.001). There were neither abnormal findings on two-dimensional echocardiography, nor pathological regurgitant signals on pulsed Doppler examination. After the inhalation of amyl nitrite, Still's murmur was accentuated by 5.3 +/- 3.0 dB, and was louder in the expiratory than in the inspiratory phase by 4.7 +/- 3.5 dB.
通过心音图研究检查了斯蒂尔杂音的发生率，并使用药效心音图和超声心动图研究了该杂音的临床意义。在9478例学童中，有224例（2.4%）存在斯蒂尔杂音。在4524例小学生中，其发生率为143例（3.2%），显著高于4954例中学生中的81例（1.6%）（p<0.001）。二维超声心动图未发现异常，脉冲多普勒检查也未发现病理性反流信号。吸入亚硝酸异戊酯后，斯蒂尔杂音增强了5.3±3.0dB，呼气期比吸气期响亮4.7±3.5dB。
