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通过放射学参数评估的骨折复位质量及其对Pilon骨折患者功能结果的影响——一项前瞻性多中心研究

Quality of fracture reduction assessed by radiological parameters and its influence on functional results in patients with pilon fractures-A prospective multicentre study.

作者信息

Sommer Christoph, Nork Sean E, Graves Matthew, Blauth Michael, Rudin Mark, Stoffel Karl

机构信息

Department of Surgery, Kantonsspital Graubuenden, Switzerland.

Department of Orthopaedic Surgery, Harborview Medical Center, USA.

出版信息

Injury. 2017 Dec;48(12):2853-2863. doi: 10.1016/j.injury.2017.10.031. Epub 2017 Oct 20.

Abstract

INTRODUCTION

The management of pilon fractures remains a challenging issue. Due to the complexity of factors that influence the outcome, it has been questioned if anatomical reductions of articular fracture are relevant. The lack of a commonly accepted assessment of quality of fracture reduction compounded the uncertainty of the importance of anatomical reduction in pilon fracture. The current study aimed to define parameters that can better assess the reduction quality and to investigate the influence of reduction quality on functional outcomes.

METHODS

Patients with unilateral pilon fracture of the AO/OTA type 43-B or 43-C were consecutively recruited to the study and followed up for 2 years after surgery. Postoperative radiographs of the injured and the contralateral joints were evaluated and 13 radiological parameters measured by 2 independent surgeons. The reliability of the measurements for each parameter was assessed by the Intraclass Correlation Coefficient (ICC), and 4 parameters with the highest ICC scores were deemed most reliable and were selected for further analyses. Functional outcome was assessed by the Foot and Ankle Ability Measure (FAAM) for daily living and sports activities. The 4 most reliable radiologic parameters, together with 3 possible baseline confounders (age, AO/OTA fracture type, and open versus closed injury), were analysed using both univariable and multivariable analysis for their association with the FAAM scores. Secondary outcome measures including pain, ankle range of motion (ROM), quality of life (QoL), and adverse events were also reported.

RESULTS

The length of lateral malleolus (LLM), anterior distal tibia angle, anterior talar shift, and length of medial malleolus scored highest on reliability in ICC assessment (ICC=0.76, 0.72, 0.58, and 0.45, respectively). Only LLM exhibited statistical significant association with the 2-year FAAM results. At the 2-year follow-up, the injured joints on average achieved a ROM of 70.7% (95% CI=63.9-77.6) when compared to the contralateral joints, and patients did not regain the pre-injury QoL overall.

CONCLUSION

The multivariable analysis showed that LLM (independent of age, AO/OTA fracture type, and open/closed injury) was a reliable indicator of reduction quality and a prognostic factor for patient outcome in pilon fracture surgery.

摘要

引言

pilon骨折的治疗仍然是一个具有挑战性的问题。由于影响治疗结果的因素复杂,关节骨折的解剖复位是否相关一直受到质疑。缺乏对骨折复位质量的普遍接受的评估,加剧了pilon骨折解剖复位重要性的不确定性。本研究旨在确定能够更好地评估复位质量的参数,并研究复位质量对功能结果的影响。

方法

连续招募AO/OTA 43-B型或43-C型单侧pilon骨折患者,并在术后随访2年。对受伤关节和对侧关节的术后X线片进行评估,由2名独立的外科医生测量13项放射学参数。通过组内相关系数(ICC)评估每个参数测量的可靠性,选择ICC评分最高的4个参数进行进一步分析。通过足踝功能能力测量(FAAM)评估日常生活和体育活动的功能结果。使用单变量和多变量分析方法,分析4个最可靠的放射学参数以及3个可能的基线混杂因素(年龄、AO/OTA骨折类型和开放性与闭合性损伤)与FAAM评分的相关性。还报告了次要结果指标,包括疼痛、踝关节活动范围(ROM)、生活质量(QoL)和不良事件。

结果

在ICC评估中,外踝长度(LLM)、胫骨远端前角、距骨前移和内踝长度的可靠性得分最高(ICC分别为0.76、0.72、0.58和0.45)。只有LLM与2年的FAAM结果存在统计学显著关联。在2年随访时,与对侧关节相比,受伤关节的ROM平均达到70.7%(95%CI=63.9-77.6),患者总体上未恢复到受伤前的生活质量。

结论

多变量分析表明,LLM(独立于年龄、AO/OTA骨折类型和开放性/闭合性损伤)是pilon骨折手术中复位质量的可靠指标和患者预后的预测因素。

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