Department of Psychiatry, McGill University, Montreal, QC, Canada; Douglas Mental Health University Institute, Montreal, QC, Canada.
School of Psychology, Université Laval, Québec, QC, Canada; Population Health and Optimal Health Practices Branch, CHU de Québec Research Centre, Québec, QC, Canada.
Neurotoxicol Teratol. 2017 Nov;64:73-78. doi: 10.1016/j.ntt.2017.10.007. Epub 2017 Oct 24.
Frequency and quantity of alcohol consumed by women are two important indicators of the risks associated with drinking during pregnancy. Some studies have compared the validity of maternal alcohol report obtained during and after pregnancy. However, to date none have examined alcohol use in a Native Canadian population, such as the Inuit. Effective measurement methods are necessary to better understand why children from some communities seem at increased risk of alcohol-related neurodevelopmental disorders.
Prospective and retrospective drinking interviews were obtained from a sub-sample of 67 women included in the Nunavik Child Development Study (NCDS), Nunavik, Canada (1995-2010; N=248). Number of days of alcohol consumption and binge drinking (five drinks or more per episode) across pregnancy as well as ounces of absolute alcohol per day and per drinking day among users were collected using timeline follow-back interviews administered both during pregnancy and again 11years after delivery. Consistency of alcohol reports over time, as well as significant differences for alcohol quantities described by users between interviews were examined. Sociodemographic characteristics associated with alcohol use reports were also assessed.
The proportion of positive reports of alcohol and binge drinking during pregnancy was higher when women were interviewed prospectively during pregnancy than retrospectively. We observed a fair to moderate agreement of alcohol report between interview periods. By contrast, the number of binge drinking days during pregnancy was slightly higher among alcohol users when documented retrospectively.
Our findings endorse the conclusion that prospective alcohol measures provide more reliable ascertainment and likely generate more valid information about the proportion of children prenatally exposed to alcohol in the Inuit population.
女性饮酒的频率和数量是与孕期饮酒相关风险的两个重要指标。一些研究比较了孕期和产后获得的母体酒精报告的有效性。然而,迄今为止,还没有研究过加拿大原住民(如因纽特人)的饮酒情况。有效的测量方法对于更好地理解为什么来自某些社区的儿童似乎面临更高的与酒精相关的神经发育障碍风险是必要的。
前瞻性和回顾性饮酒访谈是从包括在努纳武特儿童发展研究(Nunavik Child Development Study,NCDS)中的 67 名女性亚样本中获得的(1995-2010 年;N=248)。使用时间线随访访谈收集了怀孕期间以及产后 11 年期间的饮酒天数和 binge 饮酒(每回合五杯或更多),以及使用者中每天和每个饮酒日的绝对酒精量。还检查了随着时间的推移酒精报告的一致性,以及用户在访谈之间描述的酒精数量的显著差异。还评估了与饮酒报告相关的社会人口特征。
当女性在怀孕期间进行前瞻性访谈时,报告怀孕期间饮酒和 binge 饮酒的阳性比例高于回顾性访谈。我们观察到两个访谈期间的酒精报告具有良好到中度的一致性。相比之下,当通过回顾性记录时,binge 饮酒天数在怀孕期间略高。
我们的研究结果支持这样的结论,即前瞻性酒精测量方法提供了更可靠的确定,并可能生成关于因纽特人群中产前接触酒精的儿童比例的更有效信息。