Patel Mayur, Swofford Brenen, Distler Edward
Internal Medicine, University of Arizona College of Medicine Phoenix, Phoenix, Arizona, USA.
BMJ Case Rep. 2017 Oct 27;2017:bcr-2017-221864. doi: 10.1136/bcr-2017-221864.
A 50-year-old man with a history of vasospastic angina diagnosed 3 months prior presented with recurrent episodes of substernal chest pain. His chest pain was characterised as 'squeezing', lasting 10 min and typically occurred on awakening. Medications included isosorbide, nitroglycerin and ranolazine; however, due to lack of insurance he was unable to obtain these medications. On admission, patient was given a full-dose aspirin and nitroglycerin, which acutely worsened his chest pain. ECG did not reveal ischaemic changes and initial troponin was negative. A left heart catheterisation was conducted, revealing a myocardial bridge of the mid-left anterior descending artery. Myocardial bridge, due to its rarity, is often overlooked as an aetiology for angina, myocardial ischaemia, acute coronary syndrome, syncope and cardiac death. This case highlights the importance of broadening the differential to include myocardial bridge in the work-up for chest pain, especially if nitrates worsen symptoms.
一名50岁男性,3个月前被诊断为血管痉挛性心绞痛,现出现复发性胸骨后胸痛。他的胸痛表现为“压榨性”,持续10分钟,通常在醒来时发作。用药包括异山梨酯、硝酸甘油和雷诺嗪;然而,由于没有保险,他无法获得这些药物。入院时,患者接受了全剂量阿司匹林和硝酸甘油治疗,这却使他的胸痛急性加重。心电图未显示缺血性改变,初始肌钙蛋白为阴性。进行了左心导管检查,发现左前降支中段有心肌桥。由于心肌桥较为罕见,它常被忽视作为心绞痛、心肌缺血、急性冠状动脉综合征、晕厥和心源性死亡的病因。本病例强调了在胸痛检查中扩大鉴别诊断范围以包括心肌桥的重要性,特别是当硝酸盐类药物使症状加重时。