School of Gerontology Health Management and Master's Program in Long-Term Care, College of Nursing, Taipei Medical University, Taipei, Taiwan R.O.C.
Department of International Business, Soochow University, Taipei, Taiwan R.O.C.
J Pain Symptom Manage. 2018 Mar;55(3):755-765.e5. doi: 10.1016/j.jpainsymman.2017.10.010. Epub 2018 Feb 1.
Evidence for the association of hospice exposure with lower health care expenditures at end of life (EOL) remains inconclusive and neglects EOL care being concentrated in patients' last few months.
The association between hospice exposure and health care expenditures in cancer patients' last one, three, six, and 12 months was evaluated.
In this population-based, retrospective cohort study, Taiwanese cancer decedents in 2001-2010 (N = 195,228) were matched 1:1, with proportions of matched hospice users reaching 87.8%, by a hospice-utilization propensity score. For each matched pair, exposure to hospice (time from hospice enrollment to death) was matched to equivalent periods for hospice nonusers before death. Hospice-care associations with health care expenditures were evaluated by hospice use/exposure interactions with multilevel linear regression modeling using generalized estimating equations.
The unadjusted main effect showed lower total mean health care expenditures for hospice users than for hospice nonusers only in the last one and three months (rate ratio [95% CI]: 0.86 [0.81, 0.90] and 0.93 [0.89, 0.96], respectively). However, after accounting for exposure time, hospice care was significantly associated with lower health care expenditures at exposures of ≤30, ≤60, and ≤180 days for health care expenditures measured in the last one and three months, six months, and 12 months, respectively. Savings for patients with lengthy hospice stays were neutralized or even disappeared.
Hospice care was associated with lower health care expenditures when it could actively intervene in EOL care. Hospice philosophy should be applied not only shortly before death but also throughout the dying trajectory to achieve maximum cost savings.
临终关怀服务的利用与临终阶段医疗保健支出之间的关联仍存在争议,且该争议忽视了临终关怀服务主要集中在患者生命的最后几个月这一事实。
评估癌症患者生命最后一个月、三个月、六个月和十二个月的临终关怀服务利用与医疗保健支出之间的关联。
本基于人群的回顾性队列研究,以 2001-2010 年的台湾癌症死亡患者(N=195228)为研究对象,通过临终关怀服务利用倾向评分进行 1:1 配对,匹配比例达到 87.8%。对于每一对匹配患者,将临终关怀服务的暴露(从临终关怀登记到死亡的时间)与死亡前相当的无临终关怀服务的时间段相匹配。使用广义估计方程的多层次线性回归模型评估临终关怀利用与健康保健支出之间的关联,并通过临终关怀利用与暴露的交互作用进行检验。
在未校正的主要效应中,仅在生命的最后一个月和三个月,临终关怀服务的利用与临终关怀非利用相比,总平均医疗保健支出更低(调整后比值比[95%置信区间]:0.86[0.81,0.90]和 0.93[0.89,0.96])。然而,在考虑暴露时间后,临终关怀服务与生命最后一个月和三个月、六个月和十二个月的医疗保健支出呈显著负相关,其暴露时间分别为≤30、≤60 和≤180 天。对于接受长时间临终关怀服务的患者,节省的费用被中和,甚至消失。
临终关怀服务的利用与临终关怀服务能积极干预的情况下的医疗保健支出降低有关。临终关怀理念不仅应在患者死亡前不久实施,还应贯穿整个临终过程,以实现最大的成本节约。