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[铅锌矿周边儿童血铅水平分析]

[Analysis of blood lead level of children living around lead-zinc mines].

作者信息

Luo Y C, Zhao H Y, Zhu W M, Ruan B, Qiu W, Li L

机构信息

Department of occupational medicine, the Third People's Hospital of Yunnan Province, Kunming 650011, China.

出版信息

Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2017 Aug 20;35(8):571-574. doi: 10.3760/cma.j.issn.1001-9391.2017.08.003.

Abstract

To investigate the blood lead level of children living around lead-zinc mining areas, in order to analyze its distribution features of the population. In August 2016, three natural villiages around lead-zinc mines were selected randomly as survey sites, which were grouped A, B and C according to each distances from the center field, totally 1 379 children from the three villages were selected by cluster random sampling method as the investigation subjects, and their elbow peripheral vein blood samples were collected to determine the blood lead level by graphite furnace atomic absorption spectrometry. The distribution features of blood lead in different district, gender and age groups were compared and analyzed. The median and quartile range of blood lead were 0.066 and 0.058 mg/L respectively. The blood lead levels of 341 children were esceeding 100 μg/L and that account for 24.73%. The median blood lead showed statistical significant differrnce among three groups (<0.01) , and the medians from high to low were: 0.075 mg/L (A) , 0.065 mg/L (B) and 0.059 mg/L (C) respectively. The average blood lead of male was higher than that of female (<0.01) . There was significant difference in blood lead levels among different aged groups (<0.01) , and the high blood lead rate dicreased with the increase of age (<0.01) . Results of multivariate logistic regression analysis showed that there was a high risk of excessive lead in the blood lead of boys aged 1-6 years from the center of the area. The blood lead level of children living around lead-zinc mining areas is relatively high. There are difference in district distribution, gender and age.

摘要

为调查铅锌矿区周边儿童的血铅水平,分析其人群分布特征。2016年8月,随机选取铅锌矿周边3个自然村作为调查点,按距中心场地的距离分为A、B、C组,采用整群随机抽样方法从3个村共选取1379名儿童作为调查对象,采集其肘静脉外周血样,用石墨炉原子吸收光谱法测定血铅水平。比较分析不同区域、性别和年龄组血铅的分布特征。血铅中位数和四分位数间距分别为0.066和0.058mg/L。341名儿童血铅水平超过100μg/L,占24.73%。三组血铅中位数差异有统计学意义(<0.01),从高到低依次为:0.075mg/L(A组)、0.065mg/L(B组)和0.059mg/L(C组)。男性平均血铅高于女性(<0.01)。不同年龄组血铅水平差异有统计学意义(<0.01),高血铅率随年龄增长而降低(<0.01)。多因素logistic回归分析结果显示,距区域中心1 - 6岁男孩血铅超标风险高。铅锌矿区周边儿童血铅水平相对较高,在区域分布、性别和年龄方面存在差异。

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