Kershaw C J, Bulstrode C J
Accident Service, John Radcliffe Hospital, Headington, Oxford, UK.
Postgrad Med J. 1988 Oct;64(756):812-3. doi: 10.1136/pgmj.64.756.812.
A 47 year old male insulin-dependent diabetic developed two synchronous life-threatening Clostridium perfringens infections under unusual circumstances. Numerous sterile abscesses were also present, being the result of regular pentazocine intramuscular injections. Extensive surgical debridement and parenteral antibiotic therapy proved effective in treating the septicaemia and the large soft tissue abscesses in the buttock and thigh. The patient made an excellent functional recovery. The pathogenesis of gas gangrene after injection is discussed with particular reference to the diabetic patient.
一名47岁的男性胰岛素依赖型糖尿病患者在不同寻常的情况下发生了两例同时出现的危及生命的产气荚膜梭菌感染。还存在许多无菌性脓肿，这是定期肌肉注射喷他佐辛的结果。广泛的手术清创和肠外抗生素治疗被证明对治疗败血症以及臀部和大腿的大软组织脓肿有效。患者功能恢复良好。文中特别参考糖尿病患者讨论了注射后气性坏疽的发病机制。
