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真空辅助腹部闭合术安全有效:对74例连续患者的队列研究

Vacuum-Assisted Abdominal Closure Is Safe and Effective: A Cohort Study in 74 Consecutive Patients.

作者信息

Jensen R O, Buchbjerg T, Simonsen R M, Eckardt R, Qvist N

机构信息

Department of Surgery, OUH, Sdr. Boulevard 29, 5000 Odense C, Denmark.

出版信息

Surg Res Pract. 2017;2017:7845963. doi: 10.1155/2017/7845963. Epub 2017 Sep 11.

Abstract

BACKGROUND

Vacuum-assisted closure (VAC) has, in many instances, become the treatment of choice in patients with abdominal catastrophes. This study describes the use and outcome of ABThera KCI® VAC in the Region Southern Denmark covering a population of approximately 1.202 mill inhabitants.

METHOD

A prospective multicenter study including all patients treated with VAC during an eleven-month period.

RESULTS

A total of 74 consecutive patients were included. Median age was 64.4 (9-89) years, 64% were men, and median body mass index was 25 (17-42). Duration of VAC treatment was median 4.5 (0-39) days with median 1 (0-16) dressing changes. Seventy per cent of the patients attended the intensive care unit. The 90-day mortality was 15%. A secondary closure of the fascia was obtained in 84% of the surviving patients. Only one patient developed an enteroatmospheric fistula. Patients with secondary closure were less likely to develop large hernias and had better self-evaluated physical health score ( < 0,05). No difference in mental health was found.

CONCLUSION

The abdominal VAC treatment in patients with abdominal catastrophes is safe and with a relative low complication rate. Whether it might be superior to conventional treatment with primary closure when possible has yet to be proven in a randomized study.

摘要

背景

在许多情况下,负压封闭引流(VAC)已成为腹部严重创伤患者的首选治疗方法。本研究描述了丹麦南部地区使用KCI公司的ABThera VAC的情况及治疗结果,该地区人口约120.2万。

方法

一项前瞻性多中心研究,纳入了在11个月期间接受VAC治疗的所有患者。

结果

共纳入74例连续患者。中位年龄为64.4岁(9 - 89岁),64%为男性,中位体重指数为25(17 - 42)。VAC治疗持续时间中位为4.5天(0 - 39天),中位换药次数为1次(0 - 16次)。70%的患者入住重症监护病房。90天死亡率为15%。84%的存活患者实现了筋膜二期缝合。仅1例患者发生肠腹壁瘘。接受二期缝合的患者发生大疝的可能性较小,且自我评估的身体健康评分更好(<0.05)。心理健康方面未发现差异。

结论

腹部严重创伤患者的腹部VAC治疗是安全的,并发症发生率相对较低。在随机研究中,它是否可能优于可能的一期缝合传统治疗方法还有待证实。

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Are commercial negative pressure systems worth the cost in open abdomen management?商业负压系统在开放性腹部管理中是否值得花费?
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