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门诊产后抗生素处方:确定需要改进的感染控制区域的方法和验证感染登记的敏感性。

Outpatient post-partum antibiotic prescription: method of identification of infection control areas demanding improvements and verification of sensitivity of infection registration.

机构信息

Chair of Microbiology, Jagiellonian University Medical College, Krakow, Poland.

Department of Epidemiology, and Preventive Medicine, Jagiellonian University Medical College, Krakow, Poland.

出版信息

J Antimicrob Chemother. 2018 Jan 1;73(1):240-245. doi: 10.1093/jac/dkx369.

DOI:10.1093/jac/dkx369
PMID:29088428
Abstract

OBJECTIVES

To evaluate data on outpatient antibiotic use in women post-labour as a potential method of monitoring infections in this group of patients.

METHODS

Demographic and antibiotic prescription data originated from the registries of the National Health Fund (pol. Narodowy Fundusz Zdrowia). The measure of antibiotic use in this study was the percentage of women who purchased the drugs from prescriptions and DDDs.

RESULTS

Among 67917 females who gave birth in the years 2013-14, 5050 (7.4%) purchased antibiotics prescribed by the obstetrician only. The average number of antibiotics bought per person was equivalent to ∼14 DDDs; in most cases (95.7%) these were β-lactams. Antibiotic use occurred significantly more frequently among younger patients (11.5% patients <18 years of age), those living in rural areas (8.2%) and those who underwent Caesarean section (8.1%). No significant differences were found between the reported day of labour and the post-partum use of antibiotics.

CONCLUSIONS

Antibiotic prescribing data can be used to verify/complement the information originating from hospital infection registries to monitor rates of infection in obstetric patients.

摘要

目的

评估产后门诊女性使用抗生素的数据,作为监测该人群感染的潜在方法。

方法

人口统计学和抗生素处方数据来源于国家健康基金(波兰语:Narodowy Fundusz Zdrowia)的登记处。本研究中抗生素使用的衡量标准是从处方和限定日剂量(DDD)购买药物的女性比例。

结果

在 2013-2014 年分娩的 67917 名女性中,有 5050 名(7.4%)购买了产科医生开的抗生素。每人购买的抗生素平均数量相当于约 14 DDD;在大多数情况下(95.7%)为β-内酰胺类抗生素。抗生素的使用在年龄较小的患者(11.5%的患者年龄<18 岁)、农村地区的患者(8.2%)和接受剖宫产的患者(8.1%)中更为常见。报告的分娩日和产后使用抗生素之间没有发现显著差异。

结论

抗生素处方数据可用于验证/补充来源于医院感染登记处的信息,以监测产科患者的感染率。

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