Seroussi R E, Krag M H, Muller D L, Pope M H
McClure Musculoskeletal Research Center, Department of Orthopaedics and Rehabilitation, University of Vermont, Burlington 05405.
J Orthop Res. 1989;7(1):122-31. doi: 10.1002/jor.1100070117.
Three rows of six evenly spaced 0.5 mm metal beads were implanted midsagittally into the discs of ten L4-5 human lumbar motion segments. The intradiscal bead displacements in response to compression, flexion, and extension loads were obtained by digitizing the bead positions from sagittal plane radiographs taken before and during the load application. Each disc was denucleated and the loading process was repeated. For the intact discs, in compression, the intradiscal bead displacements were predominantly anterior. In flexion, the beads in the center of the disc moved posteriorly whereas the beads closer to the periphery of the disc moved anteriorly. In extension, the central beads moved anteriorly and the beads closer to the periphery of the disc moved posteriorly. After denucleation, the bead displacements for compression and flexion implied an inward bulging of the inner wall of the annulus, despite outward bulging of the disc surface. We hypothesize that the inward bulging causes radial tensile stresses within the disc, leading to disruption of adjacent layers of annulus.
将三排，每排六个、间距均匀为0.5毫米的金属珠矢状面植入十个L4 - 5节段的人体腰椎运动节段的椎间盘内。通过对加载前和加载过程中矢状面X线片上的珠子位置进行数字化处理，获取椎间盘内珠子在压缩、前屈和后伸负荷作用下的位移。每个椎间盘均行髓核摘除术，然后重复加载过程。对于完整椎间盘，在压缩时，椎间盘内珠子位移主要向前。在前屈时，椎间盘中央的珠子向后移动，而靠近椎间盘周边的珠子向前移动。在后伸时，中央珠子向前移动，靠近椎间盘周边的珠子向后移动。髓核摘除术后，压缩和前屈时珠子的位移表明，尽管椎间盘表面向外膨出，但纤维环内壁向内膨出。我们推测，这种向内膨出会在椎间盘内产生径向拉应力，导致相邻纤维环层的破坏。
