Stadelmann Marc A, Stocker Roland, Maquer Ghislain, Hoppe Sven, Vermathen Peter, Alkalay Ron N, Zysset Philippe K
ARTORG Center for Biomedical Engineering Research, University of Bern, Bern, Switzerland.
Department of Orthopedic Surgery, Bern University Hospital, Bern, Switzerland.
Comput Methods Biomech Biomed Engin. 2020 Oct;23(13):934-944. doi: 10.1080/10255842.2020.1773808. Epub 2020 Jun 16.
Finite element (FE) models can unravel the link between intervertebral disc (IVD) degeneration and its mechanical behaviour. Nucleotomy may provide the data required for model verification. Three human IVDs were scanned with MRI and tested in multiple loading scenarios, prior and post nucleotomy. The resulting data was used to generate, calibrate, and verify the FE models. Nucleotomy increased the experimental range of motion by 26%, a result reproduced by the FE simulation within a 5% error. This work demonstrates the ability of FE models to reproduce the mechanical compliance of human IVDs prior and post nucleotomy.
有限元（FE）模型可以揭示椎间盘（IVD）退变与其力学行为之间的联系。髓核摘除术可能提供模型验证所需的数据。对三个人类椎间盘进行了磁共振成像（MRI）扫描，并在髓核摘除术前和术后的多种加载情况下进行了测试。所得数据用于生成、校准和验证有限元模型。髓核摘除术使实验活动范围增加了26%，有限元模拟再现了这一结果，误差在5%以内。这项工作证明了有限元模型能够再现人类椎间盘在髓核摘除术前和术后的力学顺应性。
