Hutcherson Timothy C, Cieri-Hutcherson Nicole E, Bhatt Rajvi
P T. 2017 Nov;42(11):692-698.
Idarucizumab is the first reversal agent approved for the direct thrombin inhibitor dabigatran. The authors summarize the findings from the clinical trial series and describe case reports, post-marketing data, and ongoing studies.
依达赛珠单抗是首个被批准用于直接凝血酶抑制剂达比加群的逆转剂。作者总结了临床试验系列的结果,并描述了病例报告、上市后数据和正在进行的研究。