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Neuroprotective Functions for the Histone Deacetylase SIRT6.组蛋白去乙酰化酶SIRT6的神经保护功能
Cell Rep. 2017 Mar 28;18(13):3052-3062. doi: 10.1016/j.celrep.2017.03.008.
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Nuclear Tau and Its Potential Role in Alzheimer's Disease.核 Tau 蛋白及其在阿尔茨海默病中的潜在作用。
Biomolecules. 2016 Jan 7;6(1):9. doi: 10.3390/biom6010009.
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The multifaceted functions of sirtuins in cancer.Sirtuins 在癌症中的多方面功能。
Nat Rev Cancer. 2015 Oct;15(10):608-24. doi: 10.1038/nrc3985. Epub 2015 Sep 18.
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DNA damage and its links to neurodegeneration.DNA 损伤及其与神经退行性变的关系。
Neuron. 2014 Jul 16;83(2):266-282. doi: 10.1016/j.neuron.2014.06.034.
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Chromatin and beyond: the multitasking roles for SIRT6.染色质及其他：SIRT6 的多重任务角色。
Trends Biochem Sci. 2014 Feb;39(2):72-81. doi: 10.1016/j.tibs.2013.12.002. Epub 2014 Jan 14.
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Correlation of Alzheimer disease neuropathologic changes with cognitive status: a review of the literature.阿尔茨海默病神经病理变化与认知状态的相关性：文献综述。
J Neuropathol Exp Neurol. 2012 May;71(5):362-81. doi: 10.1097/NEN.0b013e31825018f7.
7
Amyloid-β/Fyn-induced synaptic, network, and cognitive impairments depend on tau levels in multiple mouse models of Alzheimer's disease.淀粉样蛋白-β/Fyn 诱导的突触、网络和认知障碍依赖于阿尔茨海默病多种小鼠模型中的 tau 水平。
J Neurosci. 2011 Jan 12;31(2):700-11. doi: 10.1523/JNEUROSCI.4152-10.2011.
8
The DNA damage response: making it safe to play with knives.DNA 损伤反应：让“玩刀”变得安全。
Mol Cell. 2010 Oct 22;40(2):179-204. doi: 10.1016/j.molcel.2010.09.019.
9
Mice expressing the A53T mutant form of human alpha-synuclein exhibit hyperactivity and reduced anxiety-like behavior.表达人类α-突触核蛋白 A53T 突变体的小鼠表现出过度活跃和焦虑样行为减少。
J Neurosci Res. 2010 Jun;88(8):1777-83. doi: 10.1002/jnr.22331.
10
Abnormal social behavior, hyperactivity, impaired remote spatial memory, and increased D1-mediated dopaminergic signaling in neuronal nitric oxide synthase knockout mice.神经元型一氧化氮合酶敲除小鼠表现出异常的社交行为、多动、远程空间记忆受损和 D1 介导的多巴胺能信号增强。
Mol Brain. 2009 Jun 18;2:19. doi: 10.1186/1756-6606-2-19.

DNA damage and neurodegeneration: the unusual suspect.

作者信息

Stein Daniel, Toiber Debra

机构信息

Department of Life Sciences, Ben-Gurion University of the Negev, Beer Sheva, Israel; The Zlotowski Center for Neuroscience, Ben-Gurion University of the Negev, Beer-Sheva, Israel.

出版信息

Neural Regen Res. 2017 Sep;12(9):1441-1442. doi: 10.4103/1673-5374.215254.

DOI:10.4103/1673-5374.215254
PMID:29089988
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5649463/
Abstract
摘要