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使用计算流体-结构相互作用分析研究微型螺钉辅助快速腭扩展对阻塞性睡眠呼吸暂停综合征成年患者上气道气流的影响。

Investigation of the effects of miniscrew-assisted rapid palatal expansion on airflow in the upper airway of an adult patient with obstructive sleep apnea syndrome using computational fluid-structure interaction analysis.

作者信息

Hur Jae-Sik, Kim Hyoung-Ho, Choi Jin-Young, Suh Sang-Ho, Baek Seung-Hak

机构信息

Department of Orthodontics, School of Dentistry, Seoul National University, Seoul, Korea.

Department of Mechanical Engineering, Soongsil University, Seoul, Korea.

出版信息

Korean J Orthod. 2017 Nov;47(6):353-364. doi: 10.4041/kjod.2017.47.6.353. Epub 2017 Sep 29.

DOI:10.4041/kjod.2017.47.6.353
PMID:29090123
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5653684/
Abstract

OBJECTIVE

The objective of this study was to investigate the effects of miniscrew-assisted rapid palatal expansion (MARPE) on changes in airflow in the upper airway (UA) of an adult patient with obstructive sleep apnea syndrome (OSAS) using computational fluid-structure interaction analysis.

METHODS

Three-dimensional UA models fabricated from cone beam computed tomography images obtained before (T0) and after (T1) MARPE in an adult patient with OSAS were used for computational fluid dynamics with fluid-structure interaction analysis. Seven and nine cross-sectional planes (interplane distance of 10 mm) in the nasal cavity (NC) and pharynx, respectively, were set along UA. Changes in the cross-sectional area and changes in airflow velocity and pressure, node displacement, and total resistance at maximum inspiration (MI), rest, and maximum expiration (ME) were investigated at each plane after MARPE.

RESULTS

The cross-sectional areas at most planes in NC and the upper half of the pharynx were significantly increased at T1. Moreover, airflow velocity decreased in the anterior NC at MI and ME and in the nasopharynx and oropharynx at MI. The decrease in velocity was greater in NC than in the pharynx. The airflow pressure in the anterior NC and entire pharynx exhibited a decrease at T1. The amount of node displacement in NC and the pharynx was insignificant at both T0 and T1. Absolute values for the total resistance at MI, rest, and ME were lower at T1 than at T0.

CONCLUSIONS

MARPE improves airflow and decreases resistance in UA; therefore, it may be an effective treatment modality for adult patients with moderate OSAS.

摘要

目的

本研究的目的是使用计算流体-结构相互作用分析,探讨微型螺钉辅助快速腭扩展(MARPE)对阻塞性睡眠呼吸暂停综合征(OSAS)成年患者上气道(UA)气流变化的影响。

方法

利用一名成年OSAS患者在MARPE治疗前(T0)和治疗后(T1)获得的锥束计算机断层扫描图像构建的三维UA模型,进行流体-结构相互作用分析的计算流体动力学研究。沿UA在鼻腔(NC)和咽部分别设置7个和9个横断面(平面间距为10 mm)。研究MARPE后每个平面在最大吸气(MI)、静息和最大呼气(ME)时的横截面积变化、气流速度和压力变化、节点位移以及总阻力。

结果

T1时,NC和咽部上半部分大多数平面的横截面积显著增加。此外,在MI和ME时,NC前部以及在MI时鼻咽部和口咽部的气流速度降低。NC中速度的降低比咽部更明显。T1时,NC前部和整个咽部的气流压力均降低。在T0和T1时,NC和咽部的节点位移量均不显著。T1时MI、静息和ME时的总阻力绝对值低于T0。

结论

MARPE可改善UA的气流并降低阻力;因此,它可能是成年中度OSAS患者的一种有效治疗方式。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9df6/5653684/e498d2844e49/kjod-47-353-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9df6/5653684/b3e880725bef/kjod-47-353-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9df6/5653684/88e453f880b0/kjod-47-353-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9df6/5653684/c11d5cb1b834/kjod-47-353-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9df6/5653684/fcfa9131c212/kjod-47-353-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9df6/5653684/e498d2844e49/kjod-47-353-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9df6/5653684/b3e880725bef/kjod-47-353-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9df6/5653684/88e453f880b0/kjod-47-353-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9df6/5653684/c11d5cb1b834/kjod-47-353-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9df6/5653684/fcfa9131c212/kjod-47-353-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9df6/5653684/e498d2844e49/kjod-47-353-g005.jpg

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