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腹横肌平面阻滞在腹疝修补术后的镇痛效果:一项前瞻性、随机、对照临床试验。

Postoperative analgesic efficiency of transversus abdominis plane block after ventral hernia repair: a prospective, randomized, controlled clinical trial.

作者信息

Chesov Ion, Belîi Adrian

机构信息

"Valeriu Ghereg" Department of Anaesthesiology and Reanimatology, "Nicolae Testemitanu" State University of Medicine and Pharmacy, Chisinau, Republic of Moldova.

出版信息

Rom J Anaesth Intensive Care. 2017 Oct;24(2):125-132. doi: 10.21454/rjaic.7518.242.chv.

Abstract

BACKGROUND AND AIMS

Effective postoperative analgesia is a key element in reducing postoperative morbidity, accelerating recovery and avoiding chronic postoperative pain. The aim of this study was to evaluate the effectiveness of ultrasound-guided Transversus Abdominis Plane (TAP) block, performed before surgical incision, in providing postoperative analgesia for patients undergoing open ventral hernia repair under general anaesthesia.

METHODS

Seventy elective patients scheduled for open ventral hernia repair surgery under general anaesthesia were divided randomly into two equal groups: Group I received bilateral TAP block performed before surgical incision (n = 35); Group II received systemic postoperative analgesia with parenteral opioid (morphine) alone (n = 35). Postoperatively pain scores at rest and with movement, total morphine consumption and opioid related side effects were recorded.

RESULTS

Postoperative pain scores at rest and mobilization/cough were significantly higher in patients without TAP block (p < 0.05). Mean intraoperative fentanyl consumption was comparable between the two groups: 0.75 ± 0.31 mg in group I (TAP) and 0.86 ± 0.29 mg in group II (MO), p = 0.1299. Patients undergoing preincisional TAP block had reduced morphine requirements during the first 24 hours after surgery, compared to patients from group II, without TAP block (p = 0.0001). There was no difference in the incidence of opioid related side effects (nausea, vomiting) in the both groups during the first 24 postoperative hours.

CONCLUSION

The use of preincisional ultrasound guided TAP block reduced the pain scores at rest and with movement/cough, opioid consumption and opioid-related side effects after ventral hernia repair when compared with opioid-only analgesia.

摘要

背景与目的

有效的术后镇痛是降低术后发病率、加速康复以及避免慢性术后疼痛的关键因素。本研究旨在评估在手术切口前进行超声引导下腹横肌平面(TAP)阻滞,为全身麻醉下接受开放性腹疝修补术的患者提供术后镇痛的效果。

方法

70例计划在全身麻醉下接受开放性腹疝修补手术的择期患者被随机分为两组,每组35例:第一组在手术切口前接受双侧TAP阻滞;第二组仅接受术后静脉注射阿片类药物(吗啡)的全身镇痛。记录术后静息和活动时的疼痛评分、吗啡总消耗量以及与阿片类药物相关的副作用。

结果

未接受TAP阻滞的患者术后静息和活动/咳嗽时的疼痛评分显著更高(p<0.05)。两组术中芬太尼平均消耗量相当:第一组(TAP组)为0.75±0.31mg,第二组(吗啡组)为0.86±0.29mg,p=0.1299。与未接受TAP阻滞的第二组患者相比,接受切口前TAP阻滞的患者术后24小时内吗啡需求量减少(p=0.0001)。术后24小时内两组阿片类药物相关副作用(恶心、呕吐)的发生率无差异。

结论

与单纯阿片类药物镇痛相比,切口前超声引导下TAP阻滞可降低腹疝修补术后静息和活动/咳嗽时的疼痛评分、阿片类药物消耗量以及与阿片类药物相关的副作用。

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