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超声引导下腹横肌平面阻滞的镇痛效果——一项系统评价

Analgesic efficacy of the ultrasound-guided blockade of the transversus abdominis plane - a systematic review.

作者信息

Ripollés Javier, Mezquita Sandra Marmaña, Abad Alfredo, Calvo José

机构信息

Service of Anesthesiology and Reanimation, Hospital Universitario Infanta Leonor, Madrid, Spain.

Service of Anesthesiology and Reanimation, Hospital Universitario Moisés Broggi, Sant Joan Despí, Barcelona, Spain.

出版信息

Braz J Anesthesiol. 2015 Jul-Aug;65(4):255-80. doi: 10.1016/j.bjane.2013.10.016. Epub 2014 Oct 25.

Abstract

BACKGROUND

The transverse abdominal plan blockade is a block of abdominal wall that has diffused rapidly in the clinical practice as part of a multimodal analgesia for abdominal surgery. The performance of the ultrasound-guided technique has allowed the lowering of potential complications, as well as new approaches that were carried out according to the descriptions, and the prospective studies would make it possible to utilize the transverse abdominal plan blockade in different surgical interventions; however, the results obtained in randomized clinical trials are inconsistent.

OBJECTIVES

To prepare a systematic review aiming to determine the efficacy of the ultrasound-guided transverse abdominal plan blockade for different surgical interventions, as well as the indications according to the approaches and their influences.

METHODS

Two research approaches, one manual, and the other in Pubmed returned 28 randomized clinical trials where intervention with ultrasound-guided transverse abdominal plan blockades was performed to compare the analgesic efficacy in contrast to another technique in adults, published between 2007 and October 2013, in English or Spanish, with Jadad score>1, according to the inclusion criteria for this review. The authors analyzed independently all the randomized clinical trials.

CONCLUSIONS

The transverse abdominal plan blockades have been shown to be an effective technique in colorectal surgery, cesarean section, cholecystectomy, hysterectomy, appendectomy, donor nephrectomy, retropubic prostatectomy, and bariatric surgery. However, the data found in randomized clinical trial are not conclusive, and as a result, it is necessary to develop new and well designed randomized clinical trial, with enough statistical power to compare different approaches, drugs, doses, and volumes for the same intervention, aiming to answer the current questions and their effects in the habitual clinical practice.

摘要

背景

腹横肌平面阻滞是一种腹壁阻滞技术,作为腹部手术多模式镇痛的一部分,已在临床实践中迅速普及。超声引导技术的应用降低了潜在并发症的发生几率,同时也催生了一些根据相关描述开展的新方法,前瞻性研究将使腹横肌平面阻滞能够应用于不同的外科手术干预;然而,随机临床试验所获结果并不一致。

目的

进行一项系统评价,旨在确定超声引导下腹横肌平面阻滞用于不同外科手术干预的疗效,以及根据不同方法及其影响确定其适应证。

方法

通过两种检索方法,一种是手工检索,另一种是在PubMed数据库中检索,共获得28项随机临床试验,这些试验对成人实施超声引导下腹横肌平面阻滞干预,并与另一种技术比较镇痛效果,研究发表于2007年至2013年10月之间,语言为英语或西班牙语,根据本评价的纳入标准,Jadad评分>1。作者独立分析了所有随机临床试验。

结论

腹横肌平面阻滞已被证明在结直肠手术、剖宫产、胆囊切除术、子宫切除术、阑尾切除术、供体肾切除术、耻骨后前列腺切除术和减肥手术中是一种有效的技术。然而,随机临床试验中所获数据并不确凿,因此,有必要开展新的、设计良好的随机临床试验,具备足够的统计学效力来比较同一干预措施的不同方法、药物、剂量和容量,旨在解答当前问题及其在常规临床实践中的效果。

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