Knight Rod, Karamouzian Mohammad, Salway Travis, Gilbert Mark, Shoveller Jean
British Columbia Centre on Substance Use, Vancouver, Canada.
School of Population and Public Health, University of British Columbia, Vancouver, Canada.
J Int AIDS Soc. 2017 Nov;20(3). doi: 10.1002/jia2.25017.
Globally, young gay, bisexual and other men who have sex with men (gbMSM) continue to experience disproportionately high rates of HIV and other sexually transmitted and blood-borne infections (STBBIs). As such, there are strong public health imperatives to evaluate innovative prevention, treatment and care interventions, including online interventions. This study reviewed and assessed the status of published research (e.g. effectiveness; acceptability; differential effects across subgroups) involving online interventions that address HIV/STBBIs among young gbMSM.
We searched Medline, Embase, PsycINFO, CINAHL, and Google Scholar to identify relevant English-language publications from inception to November 2016. Studies that assessed an online intervention regarding the prevention, care, or treatment of HIV/STBBIs were included. Studies with <50% gbMSM or with a mean age ≥30 years were excluded.
Of the 3465 articles screened, 17 studies met inclusion criteria. Sixteen studies assessed interventions at the "proof-of-concept" phase, while one study assessed an intervention in the dissemination phase. All of the studies focused on behavioural or knowledge outcomes at the individual level (e.g. condom use, testing behaviour), and all but one reported a statistically significant effect on ≥1 primary outcomes. Twelve studies described theory-based interventions. Twelve were conducted in the United States, with study samples focusing mainly on White, African-American and/or Latino populations; the remaining were conducted in Hong Kong, Peru, China, and Thailand. Thirteen studies included gay and bisexual men; four studies did not assess sexual identity. Two studies reported including both HIV+ and HIV- participants, and all but one study included one or more measure of socio-economic status. Few studies reported on the differential intervention effects by socio-economic status, sexual identity, race or serostatus.
While online interventions show promise at addressing HIV/STBBI among young gbMSM, to date, little emphasis has been placed on assessing: (i) potential differential effects of interventions across subgroups of young gbMSM; (ii) effectiveness studies of interventions in the dissemination phase; and (iii) on some "key" populations of young gbMSM (e.g. those who are: transgender, from low-income settings and/or HIV positive). Future research that unpacks the potentially distinctive experiences of particular subgroups with "real world" interventions is needed.
在全球范围内,年轻的男同性恋者、双性恋者以及其他与男性发生性行为的男性(gbMSM)感染艾滋病毒和其他性传播及血源性感染(STBBIs)的比例仍然过高。因此,从公共卫生角度出发,迫切需要评估创新的预防、治疗和护理干预措施,包括在线干预措施。本研究回顾并评估了已发表的涉及针对年轻gbMSM群体的艾滋病毒/STBBIs在线干预措施的研究状况(如有效性、可接受性、不同亚组间的差异效应)。
我们检索了Medline、Embase、PsycINFO、CINAHL和谷歌学术,以识别从创刊至2016年11月的相关英文出版物。纳入评估艾滋病毒/STBBIs预防、护理或治疗在线干预措施的研究。排除男同性恋和双性恋男性比例低于50%或平均年龄≥30岁的研究。
在筛选的3465篇文章中,17项研究符合纳入标准。16项研究在“概念验证”阶段评估干预措施,1项研究在推广阶段评估干预措施。所有研究都聚焦于个体层面的行为或知识结果(如避孕套使用、检测行为),除1项研究外,其他所有研究均报告了对≥1项主要结果有统计学显著影响。12项研究描述了基于理论的干预措施。12项研究在美国进行,研究样本主要集中在白人、非裔美国人和/或拉丁裔人群;其余研究在香港、秘鲁、中国和泰国进行。13项研究纳入了男同性恋和双性恋男性;4项研究未评估性取向。2项研究报告纳入了艾滋病毒阳性和阴性参与者,除1项研究外,其他所有研究都纳入了一项或多项社会经济地位指标。很少有研究报告社会经济地位、性取向、种族或血清学状态对干预效果的差异。
虽然在线干预措施在解决年轻gbMSM群体的艾滋病毒/STBBIs问题上显示出前景,但迄今为止,很少有人重视评估:(i)干预措施在年轻gbMSM不同亚组间的潜在差异效应;(ii)推广阶段干预措施的有效性研究;以及(iii)年轻gbMSM的一些“关键”人群(如:跨性别者、低收入环境中的人群和/或艾滋病毒阳性者)。未来需要开展研究,通过“现实世界”的干预措施来剖析特定亚组可能存在的独特经历。