Bredin C P
Department of Respiratory Medicine, Cork Regional Hospital, Ireland.
Chest. 1989 Jan;95(1):18-20. doi: 10.1378/chest.95.1.18.
Pulmonary function was assessed in 15 patients who had undergone thoracoplasty (TPL) approximately 30 years previously. Relation was noted to extent of TPL performed, side of TPL, age at TPL, and degree of secondary scoliosis. Test results showed mixed restrictive and obstructive defects. Although extent of TPL did not correlate with current lung function values, the restrictive defect was probably caused by a mixture of (a) compression of lung by TPL and (b) fibrosis from old pulmonary tuberculosis. The obstructive defect might have been due to the TPL procedure itself or to chronic bronchitis related to (a) previous pulmonary TB or (b) cigarette smoking, since 14 subjects were former or current smokers. That Dsb was relatively preserved suggests that pulmonary hypertension as a late sequela of TPL may be reactive (secondary to hypoxemia and respiratory acidemia) rather than obliterative.
对大约30年前接受胸廓成形术(TPL)的15名患者进行了肺功能评估。研究了其与所施行胸廓成形术的范围、胸廓成形术的侧别、胸廓成形术时的年龄以及继发性脊柱侧弯程度之间的关系。测试结果显示存在混合性限制性和阻塞性缺陷。虽然胸廓成形术的范围与当前肺功能值无关,但限制性缺陷可能是由以下因素共同导致的:(a)胸廓成形术对肺的压迫,以及(b)陈旧性肺结核引起的纤维化。阻塞性缺陷可能是由于胸廓成形术本身,或者与(a)既往肺结核或(b)吸烟相关的慢性支气管炎所致,因为14名受试者为既往或当前吸烟者。弥散功能相对保留表明,胸廓成形术的晚期后遗症肺动脉高压可能是反应性的(继发于低氧血症和呼吸性酸血症)而非闭塞性的。