Ali N M, Hanna N, Hoffman J S
Department of Anesthesiology, University of Connecticut School of Medicine, Farmington 06032.
Gynecol Oncol. 1989 Jan;32(1):22-5. doi: 10.1016/0090-8258(89)90843-3.
We examined the effects of long-term percutaneous epidural catheterization for pain relief in nine terminally ill gynecologic cancer patients. All patients were free of side-effects such as respiratory depression, nausea, vomiting, urinary retention, or pruritus. Analgesia was excellent in six patients. Puncture-site skin inflammation occurred in four patients. Catheter dislodgement occurred in three patients. Although percutaneous epidural catheters were well tolerated in a few patients for an extended period of time, the frequency of catheter problems demonstrate that other methods such as catheter tunneling or implantable systems should be considered for long-term epidural administration of narcotics. This method appears to be most effective in patients suffering from pain due to nerve root involvement.
我们研究了长期经皮硬膜外导管置入术对9例晚期妇科癌症患者缓解疼痛的效果。所有患者均未出现呼吸抑制、恶心、呕吐、尿潴留或瘙痒等副作用。6例患者镇痛效果极佳。4例患者出现穿刺部位皮肤炎症。3例患者发生导管移位。尽管经皮硬膜外导管在少数患者中能长时间耐受良好,但导管问题的发生率表明,对于长期硬膜外给予麻醉药物,应考虑采用其他方法,如导管隧道置入或植入式系统。这种方法似乎对因神经根受累而疼痛的患者最为有效。