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量化并比较两种治疗床模型在容积调强放疗(VMAT)中的剂量学影响。

Quantification and comparison the dosimetric impact of two treatment couch model in VMAT.

作者信息

Zhang Ruohui, Gao Yulan, Bai Wenwen

机构信息

Department of Biomedical Engineering, Tianjin University, Tianjin, China.

Department of Radiation Oncology, The Fourth Hospital of Hebei Medical University, Shijiazhuang, China.

出版信息

J Appl Clin Med Phys. 2018 Jan;19(1):10-16. doi: 10.1002/acm2.12206. Epub 2017 Nov 2.

Abstract

The use of Monte Carlo treatment planning systems (TPS) in radiation therapy has increased the dosimetric accuracy of VMAT treatment sequences. However, this accuracy is compromised by not including the treatment couch into the treatment planning process. Therefore, the impact of the treatment couch on radiation delivery output was determined, and two different couch models (uniform couch model A vs two components model B) were included and tested in the Monaco TPS to investigate which model can better quantify the couch influence on radiation dose. Relative attenuation measurements were performed following procedures outlined by TG-176 with three phantom positions for A-B direction: on the left half (L), in the center (C) and on the right half (R) of the couch. As well as absolute dose comparison of static fields of 10 × 10 cm that were delivered through the couch tops with that calculated in the TPS with the couch model at 2 mm and 5 mm computing grid size respectively. The most severe percentage deviation was 4.60% for the phantom positioned at the left half of the couch with 5 mm grid size at gantry angle 120°. The couch model was included in the TPS with a uniform ED of 0.26 g/cm or a two component model with a fiber 0.52 g/cm and foam core 0.1 g/cm . After including the treatment couch, the maximum mean dose attenuation was reduced from 3.68% without couch included to (0.60, 0.83, 0.72, and 1.02) % for model A and model B at 2 and 5 mm voxel grid size. The results obtained showed that Model A performed better than the model B, demonstrating lower deviations from measurements and better robustness against dose grid resolution changes. Considering the results of this study, we propose the systematic introduction of the couch Model A in clinical routine. All the reported findings are valid for the Elekta iBEAM evo Extension 415 couch and these methods can also be used for other couch model.

摘要

蒙特卡洛治疗计划系统(TPS)在放射治疗中的应用提高了容积调强弧形治疗(VMAT)治疗序列的剂量测定准确性。然而,由于未将治疗床纳入治疗计划过程,这种准确性受到了影响。因此,确定了治疗床对辐射输出的影响,并在Monaco TPS中纳入并测试了两种不同的床模型(均匀床模型A与双组分模型B),以研究哪种模型能够更好地量化床对辐射剂量的影响。按照TG - 176概述的程序,在A - B方向的三个体模位置进行相对衰减测量:在床的左半部分(L)、中心(C)和右半部分(R)。还分别在2mm和5mm计算网格尺寸下,将通过床面传递的10×10cm静态野的绝对剂量与TPS中使用床模型计算的剂量进行比较。对于位于床左半部分、5mm网格尺寸、机架角度120°的体模,最严重的百分比偏差为4.60%。床模型以0.26g/cm的均匀电子密度或纤维为0.52g/cm、泡沫芯为0.1g/cm的双组分模型纳入TPS。纳入治疗床后,在2mm和5mm体素网格尺寸下,模型A和模型B的最大平均剂量衰减从未纳入床时的3.68%降至(0.60、0.83、0.72和1.02)%。所得结果表明,模型A比模型B表现更好,与测量值的偏差更小,并且对剂量网格分辨率变化具有更好的稳健性。考虑到本研究的结果,我们建议在临床常规中系统引入床模型A。所有报告的结果对于医科达iBEAM evo Extension 415治疗床是有效的,并且这些方法也可用于其他床模型。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ea68/5768035/6635c25f2787/ACM2-19-10-g001.jpg

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