Aguilar-Salmerón Raquel, Martínez-Sánchez Lídia, Broto-Sumalla Antoni, Fernández de Gamarra-Martínez Edurne, García-Pelaéz Milagros, Nogué-Xarau Santiago
Servicio de Farmacia, Hospital Universitari Dr. Josep Trueta, Girona, España.
Servicio de Urgencias de Pediatría, Hospital Sant Joan de Déu, Barcelona, España.
Emergencias. 2016 Feb;28(1):45-54.
The stocking of antidotes in various care settings is a subject of debate. A group of experts in hospital pharmacy and both adult and pediatric clinical toxicology was formed to review the Spanish and international literature on the subject with the aim of updating recommendations about which antidotes to stock and in what amounts in hospitals of different levels of complexity. The experts also considered the usual indications for the use of antidotes and dosing. The amount to have on hand was defined as enough to treat an adult weighing 70 kg for 24 hours (or 3 such adults in an A-level hospital; ie, a highly complex center or the reference hospital for an area). The group also listed 34 antidotes that B-level hospitals should stock and 22 that other types of hospital should stock. The recommendations also provide a guide for using the antidotes in the forms of presentation available in Spain in 2015, a list of their main indications and recommended doses, and specific notes on each.
在不同护理环境中储备解毒剂是一个存在争议的话题。为此成立了一个由医院药学以及成人和儿童临床毒理学专家组成的小组，对西班牙和国际上关于该主题的文献进行综述，目的是更新关于不同复杂程度医院应储备哪些解毒剂以及储备量的建议。专家们还考虑了解毒剂的常用适应证和剂量。手头应储备的量被定义为足以治疗一名体重70公斤的成年人24小时的量（或在A级医院治疗3名这样的成年人；即高度复杂的中心或某地区的参考医院）。该小组还列出了B级医院应储备的34种解毒剂以及其他类型医院应储备的22种解毒剂。这些建议还为2015年西班牙可用剂型的解毒剂使用提供了指南，列出了它们的主要适应证和推荐剂量，并对每种解毒剂给出了具体说明。
