Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, Strangeways Research Laboratory.
The Primary Care Unit, Department of Public Health and Primary Care.
Bioinformatics. 2018 Mar 15;34(6):1069-1071. doi: 10.1093/bioinformatics/btx705.
The collection, management and visualization of clinical pedigree (family history) data is a core activity in clinical genetics centres. However, clinical pedigree datasets can be difficult to manage, as they are time consuming to capture, and can be difficult to build, manipulate and visualize graphically. Several standalone graphical pedigree editors and drawing applications exist but there are no freely available lightweight graphical pedigree editors that can be easily configured and incorporated into web applications.
We developed 'pedigreejs', an interactive graphical pedigree editor written in JavaScript, which uses standard pedigree nomenclature. Pedigreejs provides an easily configurable, extensible and lightweight pedigree editor. It makes use of an open-source Javascript library to define a hierarchical layout and to produce images in scalable vector graphics (SVG) format that can be viewed and edited in web browsers.
The software is freely available under GPL licence (https://ccge-boadicea.github.io/pedigreejs/).
Supplementary data are available at Bioinformatics online.
临床家系（家族史）数据的收集、管理和可视化是临床遗传学中心的核心活动。然而，临床家系数据集难以管理，因为它们的捕获过程很耗时，并且难以构建、操作和图形化显示。虽然存在一些独立的图形化家系编辑器和绘图应用程序，但没有免费的轻量级图形化家系编辑器可以轻松配置并集成到 Web 应用程序中。
我们开发了“pedigreejs”，这是一个用 JavaScript 编写的交互式图形化家系编辑器，使用标准的家系命名法。Pedigreejs 提供了一个可轻松配置、可扩展和轻量级的家系编辑器。它利用一个开源的 JavaScript 库来定义层次布局，并以可缩放矢量图形 (SVG) 格式生成图像，这些图像可以在网络浏览器中查看和编辑。
该软件根据 GPL 许可证免费提供（https://ccge-boadicea.github.io/pedigreejs/）。
补充数据可在 Bioinformatics 在线获取。
