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八齿鼠口腔疾病的患病率及确定口腔疾病及其预后的诊断方法评估

Prevalence of dental disorders in degus and evaluation of diagnostic methods to determine dental disease and its prognosis.

作者信息

van Bolhuis Hester, van Hoffen Lotte, van Zijll Langhout Martine, van Engeldorp Gastelaars Heleen, Hendriks Wouter, Lamberts Marnix, Kik Marja

机构信息

AAP, Rescue Center for Exotic Animals, Almere, The Netherlands.

Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands.

出版信息

Vet Rec. 2017 Dec;181(23):627. doi: 10.1136/vr.104253. Epub 2017 Nov 2.

Abstract

Degus () are prone to develop dental disease with deleterious health effects. The two studies reported here aimed to determine the prevalence of dental disorders in degus and to identify and evaluate diagnostic tools for determination of prognosis of these disorders. In study A, health data from 225 degus at AAP, Rescue Center for Exotic Animals in the Netherlands, were collated and the prevalence of dental disorders and differences in sex and age at clinical onset of symptoms associated with dental disorders were described. The prevalence was 34.7 per cent and higher (P<0.01) in males than in females. The occurrence of cheek teeth malocclusion was highly positively (P<0.0001) correlated to mortality. In study B, 36 skulls were examined by macroscopic evaluation, radiography and histology. Additionally, the calcium:phosphorus (Ca:P) of mandibular bone in degus with and without dental disorders were determined. There was no significant (P=0.10) difference in Ca:P between the two groups. Quantifying mandibular apical cheek teeth elongation via macroscopic evaluation was highly correlated (P<0.01) to the results obtained via radiography. Examination for apical elongation by palpation and diagnostic imaging should be included in routine health monitoring of degus. Apical elongation appeared to develop before coronal elongation and when cheek teeth malocclusion occurred, prognosis for recovery of dental disease was poor.

摘要

八齿鼠容易患牙病,对健康产生有害影响。这里报告的两项研究旨在确定八齿鼠牙病的患病率,并识别和评估用于确定这些疾病预后的诊断工具。在研究A中,整理了荷兰异国动物救援中心AAP的225只八齿鼠的健康数据,并描述了牙病的患病率以及与牙病相关症状临床发作时的性别和年龄差异。患病率为34.7%,雄性高于雌性(P<0.01)。颊齿错牙合的发生与死亡率高度正相关(P<0.0001)。在研究B中,通过宏观评估、放射摄影和组织学检查了36个颅骨。此外,还测定了有牙病和无牙病的八齿鼠下颌骨的钙磷比(Ca:P)。两组之间的Ca:P没有显著差异(P=0.10)。通过宏观评估量化下颌尖牙伸长与通过放射摄影获得的结果高度相关(P<0.01)。在八齿鼠的常规健康监测中应包括通过触诊和诊断成像检查尖牙伸长情况。尖牙伸长似乎在冠伸长之前就已出现,当颊齿错牙合发生时,牙病恢复的预后较差。

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