Grannum D, Lashley Paula M
Department of Child Health, Queen Elizabeth Hospital, St Michael, Barbados.
Trop Doct. 2018 Jan;48(1):11-16. doi: 10.1177/0049475517740309. Epub 2017 Nov 3.
A retrospective study was conducted by examining all the medical files of all the children with sickle cell anaemia (Hb SS) admitted from 1 January 2009 to 31 December 2013. A total of 220 admission notes (59 patients aged 5 months-16 years) were analysed. Of these, 53.2% were boys; 85.8% of the patients had Hb SS. The most common reason for admission was vaso-occlusive crisis. Blood transfusions were used in 39.7% of admissions There were no deaths during the study period. We note the number of sickle cell-related admissions and morbidity has increased, along with an increase in the number of blood transfusions. The mortality rate for children with sickle cell in Barbados is low compared to other territories in the Caribbean and worldwide. The need for better comprehensive management protocols and universal screening should decrease the morbidity patterns seen in this study.
通过查阅2009年1月1日至2013年12月31日期间收治的所有镰状细胞贫血（Hb SS）患儿的全部病历进行了一项回顾性研究。共分析了220份入院记录（59例年龄在5个月至16岁之间的患者）。其中，53.2%为男孩；85.8%的患者患有Hb SS。最常见的入院原因是血管闭塞性危机。39.7%的入院患者接受了输血治疗。研究期间无死亡病例。我们注意到镰状细胞相关的入院人数和发病率有所增加，同时输血次数也有所增加。与加勒比地区其他地区及全球范围相比，巴巴多斯镰状细胞病患儿的死亡率较低。制定更好的综合管理方案和进行普遍筛查的必要性应能减少本研究中所观察到的发病模式。
