Rodríguez-Zarco Enrique, Vallejo-Benítez Ana, Farfán-López Francisco Javier, Vilches-Arenas Ángel, Pereira-Gallardo Sofía, Vázquez-Ramírez Francisco Javier
Servicio de Anatomía Patológica. Hospital Universitario Virgen Macarena. Sevilla. España.
Servicio de Anatomía Patológica. Hospital Universitario Virgen del Rocío. Sevilla. España.
Arch Esp Urol. 2017 Nov;70(9):792-796.
Two cases of metanephric adenoma are presented, a rare benign renal tumor, and a literature review is done under the current WHO classification (2016).
Standard histopathological study was performed with hematoxylin-eosin and immunohistochemistry to analyze the expression of WT, Vimentin, Racemase, CK7, CD10 and RCC.
Neoplasms of 3 and 4.5 cm, histologically, exhibiting tubulopapillary architecture. There was no evidence of significant nuclear atypia and mitotic figures. Immunohistochemical study showed positive immunoreaction for WT1 and Vimentin in tumor cells.
Two new cases of metanephric adenoma are presented and a review of the literature was performed in order to discuss the prognosis and differential diagnosis of metanephric adenoma. This is a rare tumor and its diagnosis lies on its morphology and its immunohistochemical profile.
报告两例后肾腺瘤(一种罕见的良性肾肿瘤),并根据世界卫生组织(2016年)的现行分类进行文献综述。
采用苏木精-伊红染色和免疫组织化学进行标准组织病理学研究,以分析WT、波形蛋白、消旋酶、CK7、CD10和肾细胞癌(RCC)的表达。
肿瘤大小分别为3cm和4.5cm,组织学上呈现出管状乳头结构。没有明显核异型性和有丝分裂象的证据。免疫组织化学研究显示肿瘤细胞中WT1和波形蛋白呈阳性免疫反应。
报告了两例新的后肾腺瘤病例,并进行文献综述以讨论后肾腺瘤的预后和鉴别诊断。这是一种罕见肿瘤,其诊断取决于其形态学和免疫组织化学特征。